Similar studies for GEO DataSets (Select 200064004) - GEO DataSets

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Items: 3

Select item 2000640041.

Expression data from ileum of mice suffered from subchronic and mild social defeat stress

(Submitter supplied) This study aimed to investigate the effects of depression on transcriptome in ileum using a subchronic and mild social defeat stress (sCSDS) model. In addition to exhibiting social deficit and hyperphagia-like behavior, the sCSDS mice keep much more water in their body than control mice. In order to investigate the effect of social defeat stress on not only central nervous system but also function of gastrointestinal tract, the gene expression in ileum of stressed mice was compared with control mice. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
10 Samples

Download data: CEL

Series

Accession:: GSE64004

ID:: 200064004

Select item 2000561372.

VSL#3 supplementation of mice is associated primarily with changes in ileal microbiota composition and amelioration of DSS-induced colitis.

(Submitter supplied) Inflammatory bowel diseases encompass gastrointestinal illnesseses typified by chronic inflammation, loss of epithelial integrity and gastrointestinal microbiota dysbiosis. In an effort to counteract these characteristic perturbations, we used stem cells and/or a probiotic preparation in a murine model of Dextran Sodium Sulfate induced colitis to examine both their efficacy in ameliorating disease and impact on niche-specific microbial communities of the lower GI tract. more...