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Links from GEO DataSets

Items: 20

1.

Regulatory consequences of ZNF395 knock-down in MDA-LM2-shTARBP2 cell-line

(Submitter supplied) shRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of ZNF395 resulted in a significant up-regulation in several key oncogenes.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
8 Samples
Download data: TXT
Series
Accession:
GSE49613
ID:
200049613
2.

Regulatory consequences of TARBP2 knock-down in MDA-LM2-shDicer cell-line

(Submitter supplied) siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
4 Samples
Download data: TXT
Series
Accession:
GSE56950
ID:
200056950
3.

Regulatory consequences of TARBP2 knock-down in Dicer-null MEFs

(Submitter supplied) siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
5 Samples
Download data: TXT
Series
Accession:
GSE56949
ID:
200056949
4.

Regulatory consequences of TARBP2 over-expression in MDA-231 cell-line

(Submitter supplied) Transient transfection of TARBP2 expression vectors (along with GFP controls) followed by transcriptomic profiling revealed that over-expression of TARBP2 resulted in a significant enrichment of sRSE-carrying transcripts among the down-regulated transcripts.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
4 Samples
Download data: TXT
Series
Accession:
GSE56948
ID:
200056948
5.

Regulatory consequences of TARBP2 knock-down in CN-LM1a cell-line

(Submitter supplied) siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
4 Samples
Download data: TXT
Series
Accession:
GSE56947
ID:
200056947
6.

Regulatory consequences of TARBP2 knock-down in293T cell-line

(Submitter supplied) siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
3 Samples
Download data: TXT
Series
Accession:
GSE56945
ID:
200056945
7.

Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Expression profiling by array
Platforms:
GPL10558 GPL6885 GPL11154
78 Samples
Download data
Series
Accession:
GSE49649
ID:
200049649
8.

TARBP2 HITS-CLIP

(Submitter supplied) In order to identify TARBP2 binding sites on endogenous RNA, we performed HITS-CLIP on a myc-tagged TARBP2 expressing cell-line (transient transfection)
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
2 Samples
Download data: BED
Series
Accession:
GSE49648
ID:
200049648
9.

Regulatory consequences of TARBP2 knock-down in MDA-LM2 cell-line [stability experiment]

(Submitter supplied) siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant increase in the stability of sRSE-carrying transcripts.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
8 Samples
Download data: TXT
Series
Accession:
GSE49612
ID:
200049612
10.

Regulatory consequences of TARBP2 knock-down in MDA-LM2 cell-line

(Submitter supplied) siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
4 Samples
Download data: TXT
Series
Accession:
GSE49611
ID:
200049611
11.

In-culture titration experiment for sRSE

(Submitter supplied) In order to test the transcriptome-wide functionality of the identified sRSE instances, we performed an in vivo titration experiment in which synthetic RNA oligonucleotides harboring tandem sRSE1 repeats were used as intracellular decoys that would bind the putative trans factor, preventing it from targeting endogenous transcripts.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
4 Samples
Download data: TXT
Series
Accession:
GSE49609
ID:
200049609
12.

Differential transcript stability measurements in MDA-MB-231 vs. MDA-LM2 cells

(Submitter supplied) We performed whole-genome stability measurements for MDA-MB-231 and its highly metastatic derivative MDA-LM2. Our goal was to identify post-transcriptonal regulons that are deregulated en route to higher metastatic capacity.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
32 Samples
Download data: TXT
13.

Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Expression profiling by high throughput sequencing; Other
Platforms:
GPL11154 GPL10558
16 Samples
Download data
Series
Accession:
GSE76488
ID:
200076488
14.

MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells

(Submitter supplied) To identify MBNL1-dependent changes in gene expression, MDA-MB-231 cells expressing either control or MBNL1-targeting shRNAs were transcriptomically profiled.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
6 Samples
Download data: TXT
15.

MBNL1 HITS-CLIP in MDA-MB-231 breast cancer cells

(Submitter supplied) HITS-CLIP was performed to identify endogenous MBNL1 binding sites on RNAs in MDA-MB-231 breast cancer cells.
Organism:
Homo sapiens
Type:
Other
Platform:
GPL11154
2 Samples
Download data: BED
16.

MBNL1-dependent modulation of transcript stability

(Submitter supplied) In order to identify MBNL1-dependent changes in MBNL1 target transcript stability, MBNL1 levels in MDA-MB-231 breast cancer cells were stably knocked-down using short-hairpin RNAs. The cells were then treated with alpha-amanitin to inhibit transcription, RNA was isolated at 0 and 9 hours post-alpha-amanitin treatment, and the samples were transcriptomically profiled.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
8 Samples
Download data: TXT
Series
Accession:
GSE76485
ID:
200076485
17.

SRSF1 HITS-CLIP in MDA-LM2

(Submitter supplied) To identify SRSF1 binding sites on RNAs, we performed HITS-CLIP of endogenous SRSF1 in MDA-LM2 cells
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
2 Samples
Download data: BED
18.

siRNA-mediated knockdown

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL20301 GPL18573 GPL16791
40 Samples
Download data: FPKM_TRACKING, TXT
Series
Accession:
GSE130894
ID:
200130894
19.

MeRIP-seq of control and TARBP2 knockdown cells

(Submitter supplied) To identify changes in methylation patterns following TARBP2 knockdown, m6A-IP followed by RNA-seq was performed on breast cancer cells expressing shRNAs against TARBP2 (and non-targeting shControl cells).
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
8 Samples
Download data: BED, TXT
20.

Total RNA-seq of siRNA-mediated WTAP and TPR knockdown

(Submitter supplied) To identify changes in splicing patterns following WTAP and TPR knockdown, RNA-sequencing was performed on breast cancer cells transfected with siRNAs targeting WTAP or TPR.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
6 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE130873
ID:
200130873
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