Euglycemic agent-mediated hypothalamic transcriptomic manipulation in the N171-82Q model of Huntington's disease is related to their physiological efficacy - - GEO DataSets

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Euglycemic agent-mediated hypothalamic transcriptomic manipulation in the N171-82Q model of Huntington's disease is related to their physiological efficacy

(Submitter supplied) Our aim was to find an effective treatment for the dysfunction in energy regulation and hypothalamic integrity occurring in many Huntington’s disease (HD) patients and mouse models. HD is a neurodegenerative disease caused by an expanded CAG repeat and is characterized by mutant huntingtin aggregates, cell death, progressive motor impairment, and cognitive alterations. Changes in neuroendocrine function, body weight, energy metabolism, euglycemia, appetite function, sleep, and gut function can also occur. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6885
23 Samples

Download data: TXT

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Accession:: GSE39586

ID:: 200039586

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