GEO DataSets

(Submitter supplied) Study goal is to disclose features of gene expressio profile of non-cancerous liver-infiltrating lymphocytes of type C hepatitis patients with hepatocellular carcinomas and tumor-infiltrating lymphocytes of type C hepatitis patients with hepatocellular carcinomas. Keywords: gene expression profile, non-cancerous liver-infiltrating lymphocytes, tumor-infiltrating lymphocytes, type C hepatitis, hepatocellular carcinoma

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL1291

24 Samples

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(Submitter supplied) Study goal is to disclose features of gene expression profile of peripheral blood mononuclear cells obtained from type C cirrhotic patients with or without hepatocellular carcinomas. Keywords: gene expression profile, peripheral blood mononuclear cells, type C liver cirrhosis

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL1291

62 Samples

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(Submitter supplied) The Wilms´ tumor 1 gene (WT1) encodes a transcription factor involved in cell growth and development. As we previously reported WT1 expression is hardly detectable in normal hepatic tissue but is induced in liver cirrhosis. Although WT1 has been found to be overexpressed in a number of malignancies, the role of WT1 in hepatocarcinogenesis has not been clarified. We found that WT1 is expressed in several human hepatocellular carcinoma (HCC) cell lines including PLC/PRF/5 and HepG2, and in HCC tumor tissue in 42% of patients. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

6 Samples

Download data: CEL

(Submitter supplied) Aberrant gene expression analysis between peripheral blood mononuclear cell (PBMC) samples from healthy individuals and patients with pancreatic carcinoma, gastric carcinoma and hepatocellular carcinoma (HCC) were identified using Affymetrix gene arrays.

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4882

Platform:

GPL570

26 Samples

Download data: CEL

Analysis of peripheral blood mononuclear cells from hepatocellular carcinoma (HCC), pancreatic carcinoma, and gastric carcinoma patients. Results provide insight into a blood-based gene signature for detection of early-stage HCC.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 4 disease state sets

Platform:

GPL570

Series:

GSE49515

26 Samples

Download data: CEL

(Submitter supplied) Gene expression profiling of hepatocellular carcinoma (HCC) and background liver has been studied extensively; however, the relationship between the gene expression profiles of different lesions has not been assessed. We examined the expression profiles of 34 HCC specimens (17 hepatitis B virus [HBV]-related and 17 hepatitis C virus [HCV]-related) and 71 non-tumor liver specimens (36 chronic hepatitis B [CH-B] and 35 chronic hepatitis C [CH-C]) using an in-house cDNA microarray consisting of liver-predominant genes. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL13536

105 Samples

Download data: GPR

(Submitter supplied) We performed gene expression profiling of hepatocellular carcinoma (HCC), cholangiocarcinoma (CC), and mixed type of combined HCC and CC (CHC). In comparison of the profiles, a novel class of HCC expressing CC-like traits was identified.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL571

90 Samples

Download data: CEL

(Submitter supplied) Mouse models of hepatocellular carcinoma (HCC) simulate specific subgroups of human HCC. We investigated hepatocarcinogenesis in Mdr2-KO mice, a model of inflammation-associated HCC, using gene expression profiling and immunohistochemical analyses. Gene expression profiling demonstrated that although Mdr2-KO mice differ from other published murine HCC models, they share several important deregulated pathways and many coordinately differentially expressed genes with human HCC datasets. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL339

15 Samples

Download data: CEL

(Submitter supplied) Differential gene expression analysis between chronic hepatitis B induced HCC and adjacent Normal tissues using Affymetrix gene arrays. 

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

107 Samples

Download data: CEL

(Submitter supplied) d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxicity) in brain tissue. The transcriptomic changes that occur in the brain after d-serine exposure have not been fully explored. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS3643

Platform:

GPL1355

24 Samples

Download data: CEL

Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 6 dose sets

Platform:

GPL1355

Series:

GSE10748

24 Samples

Download data: CEL

(Submitter supplied) The aim of this study was to analyze the expression profile of circRNAs in PBMCs in peripheral blood of patients with hepatocellular carcinoma (HCC) by next-generation sequencing, and to identify potential markers for early diagnosis and prognosis of HCC, and to lay a foundation for further study on the mechanism of this molecule in PBMCs.

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20795

7 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL6487 GPL6488

60 Samples

Download data: CSV

(Submitter supplied) In comparison with allogeneic hematopoietic stem cell transplantation using other sources, umbilical cord blood transplantation (UCBT) offers substantial clinical advantages including a lower incidence and severity of acute graft-versus-host disease (GVHD) despite the use of allogeneic UCB stem cells with more disparate HLA. However, detailed pathophysiology of acute GVHD developed after UCBT has not yet been clarified. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6488

40 Samples

Download data: CSV

(Submitter supplied) In comparison with allogeneic hematopoietic stem cell transplantation using other sources, umbilical cord blood transplantation (UCBT) offers substantial clinical advantages including a lower incidence and severity of acute graft-versus-host disease (GVHD) despite the use of allogeneic UCB stem cells with more disparate HLA. However, detailed pathophysiology of acute GVHD developed after UCBT has not yet been clarified. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6487

20 Samples

Download data: CSV

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL4134

51 Samples

Download data: TXT

(Submitter supplied) Chronological change of gene expression profile of Hepa1-6 tumors in C57Bl/6

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL4134

6 Samples

Download data: TXT

(Submitter supplied) Chronological change of gene expression profile of whole blood cells of C57Bl/6 with Hepa1-6 tumors

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL4134

20 Samples

Download data: TXT

(Submitter supplied) Examination of gene expression profile of blood and tumor-infiltrating inflammatory cells

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL4134

16 Samples

Download data: TXT

(Submitter supplied) Chronological change of gene expression profile of whole blood cells and features of the fraction enriched with tumor-infiltrating inflammatory cells of Balb/c athymic mice with Hepa1-6 tumors

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL4134

9 Samples

Download data: TXT