GEO DataSets

(Submitter supplied) Perturbation of the gated-synchrony system in yeast with phenelzine, an antidepressant drug used in the treatment of affective disorders in humans, leads to a rapid lengthening in the period of the genome-wide transcriptional oscillation. The effect is a concerted, genome-scale change in expression that is first seen in genes maximally expressed in the late-reductive phase of the cycle, doubling the length of the reductive phase within two cycles after treatment. more...

Organism:

Schizosaccharomyces pombe; Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL2529

48 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Schizosaccharomyces pombe; Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL2529

81 Samples

Download data: CEL

(Submitter supplied) Genetic and environmental factors influence the phenotype of an organism. Time is rarely considered when studying changes in cellular phenotype. Time-resolved microarray data revealed genome-wide transcriptional changes in cells oscillating with ~2 and ~4 h periods. We mapped the global patterns of transcriptional oscillations into a 3-dimensional map to represent different cellular phenotypes of oscillation period. more...

Organism:

Saccharomyces cerevisiae; Schizosaccharomyces pombe

Type:

Expression profiling by array

Platform:

GPL2529

49 Samples

Download data: CEL

(Submitter supplied) Genetic and environmental factors influence the phenotype of an organism. Time is rarely considered when studying changes in cellular phenotype. Time-resolved microarray data revealed genome-wide transcriptional changes in cells oscillating with ~2 and ~4 h periods. We mapped the global patterns of transcriptional oscillations into a 3-dimensional map to represent different cellular phenotypes of oscillation period. more...

Organism:

Schizosaccharomyces pombe; Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL2529

32 Samples

Download data: CEL

(Submitter supplied) In order to test the idea that the cell is an attractor and to examine in detail the connectivity relationships among genes, it was essential to have a very reproducible and precise biological system. Oscillations in respiratory activity in budding yeast and other organisms have been known for many years. This benchmark oscillation is now shown to be a global manifestation of a genome wide oscillation in transcription. more...

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL90

32 Samples

Download data: TXT

(Submitter supplied) This data set represents the results of two reverse labeled experiments from wild-type and RRP6delta S. cerevisiae that has been hybed to arrays containing PCR products for ORFs and Intergenic Features Keywords: genetic modification

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL3237

1 Sample

Download data: GPR

(Submitter supplied) Disruption of Ras/cAMP signaling by perturbation of pathway elements and controlled cAMP concentration. All cultures grown in SC medium. Keywords: other

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Dataset:

GDS1981

Platform:

GPL2622

20 Samples

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Analysis of cells following perturbation of the Ras-cAMP pathway by disrupting or constitutively activating cAMP signaling, or varying the concentration of cAMP. Results provide insight into the flow of information across a genome.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 5 agent, 7 genotype/variation, 4 protocol sets

Platform:

GPL2622

Series:

GSE2927

20 Samples

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(Submitter supplied) Time points from two separate experiments – a) every 15 min after release from the G1 block from 0 min – 105 min and b) every 5 min beginning 20 min after block (through S-phase) from 20 -50 min. Data include composite of normalized high and low scan intensities

Organism:

Saccharomyces cerevisiae

Type:

Genome binding/occupancy profiling by genome tiling array

Platform:

GPL4131

14 Samples

Download data: GPR

(Submitter supplied) Yeast grown in synthetic complete medium (SD) until glucose depletion is aged chronologically. Cells are stressed by lacking of nutrients and accumulating toxic substances, and thus undergo gene expression changes in response to those. We performed microarray experiments to capture gene expression profiles of yeast cultured at 4 different time points.

Organism:

Saccharomyces cerevisiae; Schizosaccharomyces pombe

Type:

Expression profiling by array

Platform:

GPL2529

12 Samples

Download data: CEL

(Submitter supplied) We developed a 'Virtual Northern' method, using DNA microarrays for genome-wide systematic analysis of mRNA lengths. We used this method to measure mRNAs corresponding to 84% of the annotated open reading frames (ORFs) in the S. cerevisiae genome, with high precision and accuracy (measurement errors 1 6-7%). We found a close linear relationship between mRNA lengths and the lengths of known or predicted translated sequences; mRNAs were typically around 300 nucleotides longer than the translated sequences. more...

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL3292

35 Samples

Download data

(Submitter supplied) In recent years there has been considerable and growing interest in the 3-dimensional organization of genomes. In yeast this has included detailed FISH studies that show a surprising degree of spatial clustering of the tRNA genes, the localization of telomeres, centromere positioning, and global studies of chromosomal interactions. In this study we performed an integrated biophysical – molecular study to produce the first high-resolution 3-dimensional reconstruction of a eukaryotic genome from first principles. more...

Organism:

Saccharomyces cerevisiae

Type:

Other

Platform:

GPL9134

2 Samples

Download data: TXT

(Submitter supplied) The Platform data table reflects a condensed representation of the duplicate array features. The full array layout (GPL4873_complete_layout.txt) is linked as a supplementary file at the foot of this record. Protocol: Single stranded (sense) 40mer oligonucleotides were obtained from MWG, diluted and spotted onto glass Eppendorf Creative Oligo Chips using a 24 pin ESI scanner. A total of 13824 features were spotted onto 120 slides within a run where 24 subarrays were added (6x4) with each containing 24 vertical by 24 horizontal features. more...

Organism:

Saccharomyces cerevisiae

1 DataSet

3 Series

30 Samples

Download data: TXT