GEO DataSets

(Submitter supplied) Prostate cancer is characterized by heterogeneity in the clinical course that often does not to correlate with morphologic features of the tumor. Metastasis reflects the most adverse outcome of prostate cancer, and to date there are no reliable morphologic features or serum biomarkers that can reliably predict which patients are at higher risk of developing metastatic disease. Understanding the differences in the biology of metastatic and organ confined primary tumors is essential for developing new prognostic markers and therapeutic targets. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2891

31 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array

Datasets:

GDS2545 GDS2546 GDS2547

Platforms:

GPL8300 GPL93 GPL92

504 Samples

Download data: CEL

(Submitter supplied) Prostate cancer is characterized by heterogeneity in the clinical course that often does not to correlate with morphologic features of the tumor. Metastasis reflects the most adverse outcome of prostate cancer, and to date there are no reliable morphologic features or serum biomarkers that can reliably predict which patients are at higher risk of developing metastatic disease. Understanding the differences in the biology of metastatic and organ confined primary tumors is essential for developing new prognostic markers and therapeutic targets. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL93 GPL8300 GPL92

181 Samples

Download data: CEL

(Submitter supplied) Prostate cancer is characterized by heterogeneity in the clinical course that often does not to correlate with morphologic features of the tumor. Metastasis reflects the most adverse outcome of prostate cancer, and to date there are no reliable morphologic features or serum biomarkers that can reliably predict which patients are at higher risk of developing metastatic disease. Understanding the differences in the biology of metastatic and organ confined primary tumors is essential for developing new prognostic markers and therapeutic targets. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL93 GPL8300 GPL92

196 Samples

Download data: CEL

(Submitter supplied) Prostate cancer is characterized by heterogeneity in the clinical course that often does not to correlate with morphologic features of the tumor. Metastasis reflects the most adverse outcome of prostate cancer, and to date there are no reliable morphologic features or serum biomarkers that can reliably predict which patients are at higher risk of developing metastatic disease. Understanding the differences in the biology of metastatic and organ confined primary tumors is essential for developing new prognostic markers and therapeutic targets. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL92 GPL93 GPL8300

75 Samples

Download data: CEL

(Submitter supplied) Prostate cancer is characterized by heterogeneity in the clinical course that often does not to correlate with morphologic features of the tumor. Metastasis reflects the most adverse outcome of prostate cancer, and to date there are no reliable morphologic features or serum biomarkers that can reliably predict which patients are at higher risk of developing metastatic disease. Understanding the differences in the biology of metastatic and organ confined primary tumors is essential for developing new prognostic markers and therapeutic targets. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL8300 GPL93 GPL92

52 Samples

Download data: CEL

Analysis of metastatic prostate tumors and primary prostate tumors. Normal tissue adjacent to the tumor and normal donor tissue also examined. Metastasis reflects the most adverse clinical outcome. Results provide insight into the molecular mechanisms underlying the metastatic process.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 4 tissue sets

Platform:

GPL93

Series:

GSE6919

164 Samples

Download data: CEL

Analysis of metastatic prostate tumors and primary prostate tumors. Normal tissue adjacent to the tumor and normal donor tissue also examined. Metastasis reflects the most adverse clinical outcome. Results provide insight into the molecular mechanisms underlying the metastatic process.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 4 tissue sets

Platform:

GPL92

Series:

GSE6919

167 Samples

Download data: CEL

Analysis of metastatic prostate tumors and primary prostate tumors. Normal tissue adjacent to the tumor and normal donor tissue also examined. Metastasis reflects the most adverse clinical outcome. Results provide insight into the molecular mechanisms underlying the metastatic process.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 4 tissue sets

Platform:

GPL8300

Series:

GSE6919

171 Samples

Download data: CEL

(Submitter supplied) we analyzed the gene expression profiles of Mat-Lylu cell lines (in duplicate) compared to G cell lines (in duplicate) using Affymetrix tools and dChip software. The objective was to find metastasis-associated genes in prostate cancer, using this in vitro model. Keywords: cell line comparison

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL85

4 Samples

Download data: CEL

(Submitter supplied) To identify molecular changes that occur during prostate tumor progression, we have characterized a series of prostate cancer cell lines isolated at different stages of tumorigenesis from C3(1)/Tag transgenic mice.

Organism:

Mus musculus; Homo sapiens

Type:

Expression profiling by array

Platform:

GPL20562

19 Samples

Download data: GPR

(Submitter supplied) Primary and metastatic tumor growth induce host tissue responses that are believed to support tumor progression. Understanding the molecular changes within the tumor microenvironment during tumor progression may therefore be relevant not only for discovering potential therapeutic targets but also for identifying putative molecular signatures that may improve tumor classification and predict clinical outcome. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS2443

Platform:

GPL4371

10 Samples

Download data

Analysis of laser-microdissected stromal cells from prostate intraepithelial neoplasias and invasive prostate tumors. Results provide insight into the response of stromal cells to tumor invasion.

Organism:

Mus musculus

Type:

Expression profiling by array, log2 ratio, 2 disease state sets

Platform:

GPL4371

Series:

GSE5945

10 Samples

Download data

(Submitter supplied) Gene expression profile of Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) reveals murine targets for preclinical development of human prostate cancer therapy In this study, we have generated an open source TRAMP microarray dataset to identify differentially expressed genes from human prostate cancer that have concordant expression in TRAMP tumors, and thereby represent lead targets for preclinical therapy development. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

18 Samples

Download data: CEL

(Submitter supplied) The identification of genes that contribute to the biological basis for clinical heterogeneity and progression of prostate cancer is critical to accurate classification and appropriate therapy. We performed a comprehensive gene expression analysis of prostate cancer using oligonucleotide arrays with 63,175 probe sets to identify genes and expressed sequences with strong and uniform differential expression between nonrecurrent primary prostate cancers and metastatic prostate cancers. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL91

35 Samples

Download data: CEL, RPT, TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array; Genome variation profiling by genome tiling array

Platforms:

GPL14550 GPL10123 GPL10152

56 Samples

Download data: TXT

(Submitter supplied) Prostate cancer research is hampered by a lack of preclinical models which accurately reproduce clinical heterogeneity. We have established a bank of transplantable patient-derived prostate tumor xenograft lines, using subrenal capsule grafting of human tumor tissue into immuno-deficient mice. This panel includes the first lines generated from prostate cancer biopsy tissue, and also new lines from metastatic tissue. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL14550

32 Samples

Download data: PDF, TXT

(Submitter supplied) Prostate cancer research is hampered by a lack of preclinical models which accurately reproduce clinical heterogeneity. We have established a bank of transplantable patient-derived prostate tumor xenograft lines, using subrenal capsule grafting of human tumor tissue into immuno-deficient mice. This panel includes the first lines generated from prostate cancer biopsy tissue, and also new lines from metastatic tissue. more...

Organism:

Homo sapiens

Type:

Genome variation profiling by genome tiling array

Platforms:

GPL10152 GPL10123

24 Samples

Download data: PDF, TXT

(Submitter supplied) We analysed 102 sample of mesenchymal tumors of different histological type and biological behaviour. The aim of the study was to identify genes related to each characteristic analysed.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL1930

204 Samples

Download data