Similar studies for GEO DataSets (Select 200001080) - GEO DataSets

Select item 2000010801.

Zucker diabetic fatty (ZDF)/Zucker lean control (ZLC) comparisons

(Submitter supplied) Gene expression profiles in tissues of Zucker diabetic fatty (ZDF) rats compared with age matched Zucker lean control (ZLC) rats. Keywords: other

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS1767
Platform:: GPL1002
24 Samples

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Series

Accession:: GSE1080

ID:: 200001080

Select item 17672.

Zucker diabetic fatty model of type 2 diabetes: various insulin-sensitive tissues

Analysis of adipose, skeletal muscle, and liver tissues of Zucker diabetic fatty animals at pre-diabetic and diabetic stages. ZDF animals have a mutated leptin receptor. Results provide insight into the molecular mechanisms responsible for insulin resistance and progression to type 2 diabetes.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, log ratio, 2 age, 3 tissue sets

Platform:: GPL1002
Series:: GSE1080
24 Samples

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DataSet

Accession:: GDS1767

ID:: 1767

Select item 2000238103.

Molecular studies on sex-different control of the hepatic metabolism in relations to insulin sensitivity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL6528
8 Samples

Download data: GPR

Series

Accession:: GSE23810

ID:: 200023810

Select item 2000238094.

Molecular studies on sex-different control of the hepatic metabolism in relations to insulin sensitivity (set 2)

(Submitter supplied) In this study we have analyzed gene expression and metabolite levels in the livers of male and female Zucker diabetic fatty (ZDF) rats. We speculated that the sex different development of diabetes in the ZDF animals presents the opportunity to relate gender to diabetes (since only males become diabetic on normal diet). In this model one can search for parameters that distinguish females fed normal diet compared to high fat diet (i.e. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL6528
4 Samples

Download data: GPR

Series

Accession:: GSE23809

ID:: 200023809

Select item 2000238085.

Molecular studies on sex-different control of the hepatic metabolism in relations to insulin sensitivity (set 1)

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL6528
4 Samples

Download data: GPR

Series

Accession:: GSE23808

ID:: 200023808

Select item 2000067986.

Reduced expression of mitochondrial oxidative metabolism genes in skeletal muscle of women with PCOS

(Submitter supplied) Recently, abnormalities in mitochondrial oxidative phosphorylation (OXPHOS) have been implicated in the pathogenesis of skeletal muscle insulin resistance in type 2 diabetes. In the present study, we hypothesized that decreased expression of OXPHOS genes could be of similar importance for insulin resistance in the polycystic ovary syndrome (PCOS). Using the HG-U133 Plus 2.0 expression array from Affymetrix, we analyzed gene expression in skeletal muscle from obese women with PCOS (n=16) and age- and body mass index-matched control women (n=13) metabolically characterized by euglycemic-hyperinsulinemic clamp and indirect calorimetry. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3104
Platform:: GPL570
29 Samples

Download data: CEL

Series

Accession:: GSE6798

ID:: 200006798

Select item 31047.

Insulin-resistant polycystic ovary syndrome: muscle

Analysis of vastus lateralis muscles from women with insulin-resistant polycystic ovary syndrome (PCOS). Insulin resistance in skeletal muscles is a risk factor for the development of type 2 diabetes in women with PCOS. Results provide insight into the pathogenesis of insulin resistance in PCOS.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL570
Series:: GSE6798
29 Samples

Download data: CEL

DataSet

Accession:: GDS3104

ID:: 3104

Select item 2000001218.

Type 2 diabetes and insulin resistance

(Submitter supplied) Global transcript profiling to identify differentially expressed skeletal muscle genes in insulin resistance, a major risk factor for Type II (non-insulin-dependent) diabetes mellitus. Compared gene expression profiles of skeletal muscle tissues from 18 insulin-sensitive versus 17 insulin-resistant equally obese, non-diabetic Pima Indians. Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS157 GDS158 GDS160 GDS161 GDS162
5 related Platforms
50 Samples

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Series

Accession:: GSE121

ID:: 200000121

Select item 2000000739.

Insulin resistant muscle sample pool 5

(Submitter supplied) Muscle sample pool #5 from 2 insulin resistant subjects. Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

5 related Platforms
5 Samples

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Series

Accession:: GSE73

ID:: 200000073

Select item 20000007210.

Insulin resistant muscle sample pool 4

(Submitter supplied) Muscle sample pool #4 from 3 insulin resistant subjects. Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

5 related Platforms
5 Samples

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Series

Accession:: GSE72

ID:: 200000072

Select item 20000007111.

Insulin resistant muscle sample pool 3

(Submitter supplied) Muscle sample pool #3 from 4 insulin resistant subjects. Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

5 related Platforms
5 Samples

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Series

Accession:: GSE71

ID:: 200000071

Select item 20000007012.

Insulin resistant muscle sample pool 2

(Submitter supplied) Muscle sample pool #2 from 4 insulin resistant subjects. Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

5 related Platforms
5 Samples

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Series

Accession:: GSE70

ID:: 200000070

Select item 20000006913.

Insulin resistant muscle sample pool 1

(Submitter supplied) Muscle sample pool #1 from 4 insulin resistant subjects. Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

5 related Platforms
5 Samples

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Series

Accession:: GSE69

ID:: 200000069

Select item 20000006814.

Insulin sensitive muscle sample pool 5

(Submitter supplied) Muscle sample pool #5 from 4 insulin sensitive subjects. Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

5 related Platforms
5 Samples

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Series

Accession:: GSE68

ID:: 200000068

Select item 20000006715.

Insulin sensitive muscle sample pool 4

(Submitter supplied) Muscle sample pool #4 from 3 insulin sensitive subjects. Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

5 related Platforms
5 Samples

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Series

Accession:: GSE67

ID:: 200000067

Select item 20000006616.

Insulin sensitive muscle sample pool 3

(Submitter supplied) Muscle sample pool #3 from 3 insulin sensitive subjects. Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

5 related Platforms
5 Samples

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Series

Accession:: GSE66

ID:: 200000066

Select item 20000006517.

Insulin sensitive muscle sample pool 2

(Submitter supplied) Muscle sample pool #2 from 4 insulin sensitive subjects. Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

5 related Platforms
5 Samples

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Series

Accession:: GSE65

ID:: 200000065

Select item 20000006418.

Insulin sensitive muscle sample pool 1

(Submitter supplied) Muscle sample pool #1 from 4 insulin sensitive subjects. Keywords: parallel sample

Organism:: Homo sapiens

Type:: Expression profiling by array

5 related Platforms
5 Samples

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Series

Accession:: GSE64

ID:: 200000064

Select item 16219.

Type 2 diabetes and insulin resistance (Hu35k-D)

Analysis of gene expression in pooled vastus lateralis muscle samples from insulin-sensitive and insulin-resistant equally obese, non-diabetic Pima Indians. A search for susceptibility genes for type 2 diabetes.