GEO DataSets

Analysis of Oregon R animals treated with an ethylacetate extract from Piper nigrum seeds, natural pyrethrum, or both. Pyrethrum is an insecticide. The P. nigrum extract has insecticidal properties. The study examines the synergistic effect of both agents on gene expression.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, log2 ratio, 3 agent sets

Platform:

GPL1473

Series:

GSE3035

20 Samples

Download data: TIFF

(Submitter supplied) This experiment compared separate pools of Drosophila which received identical topical treatments of 99% ethanol 6 hours after exposure. The purpose of this was to assess the degree of natural variability that could be expected to be observed between samples in the absence of distince treatments. This was to allow for greater confidence in interpreting the results of other experiments which compared insects that received different treatments. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1473

8 Samples

Download data: TIFF

(Submitter supplied) The purpose of this experiment was to assess the effect of a synergistic combination of natural pyrethrin and an ethylacetate extract of Piper nigrum seeds (a botanical insecticide). This effect was compared to the effects of P. nigrum or pyrethrin used alone. Due to the synergistic nature of the mixture, it was predicted that gene expression profiles in this treatment would reflect this effect. Keywords: insecticide response, stress-response

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Dataset:

GDS1911

Platform:

GPL1473

20 Samples

Download data: TIFF

(Submitter supplied) This experiment was intended to determine if topical exposure to ethanol led to significant changes in gene expression in adult Drosophila melanogaster. It was determined that topical exposure to ethanol did not lead to a strong differential expression of genes in Drosophila after 4 hours. Keywords: Ethanol response, stress response

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1473

2 Samples

Download data: TIFF

(Submitter supplied) I hypothesized that social interactions, such as those involved in reproductive behaviors, would lead to immediate and assayable changes in gene expression that may have important effects on individual reproductive success and fitness through alterations in physiology or via short-term or long-term changes in nervous system function. Keywords: exposed compared to unexposed treatment

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL72

6 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Drosophila simulans x Drosophila mauritiana; Drosophila melanogaster; Drosophila mauritiana; Drosophila sechellia; Drosophila simulans; Drosophila sechellia x Drosophila simulans

Type:

Expression profiling by array

Platforms:

GPL4022 GPL3829

128 Samples

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(Submitter supplied) Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in 4 day old sterile male F1 hybrids of Drosophila simulans and its sibling species, D. more...

Organism:

Drosophila melanogaster; Drosophila sechellia; Drosophila simulans; Drosophila sechellia x Drosophila simulans

Type:

Expression profiling by array

Platform:

GPL3829

22 Samples

Download data

(Submitter supplied) Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in 4 day old sterile male F1 hybrids of Drosophila simulans and its sibling species, D. more...

Organism:

Drosophila mauritiana; Drosophila simulans x Drosophila mauritiana; Drosophila simulans; Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL3829

22 Samples

Download data

(Submitter supplied) Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in 4 day old sterile male F1 hybrids of Drosophila simulans and its sibling species, D. more...

Organism:

Drosophila simulans; Drosophila sechellia x Drosophila simulans; Drosophila sechellia; Drosophila mauritiana

Type:

Expression profiling by array

Platform:

GPL4022

22 Samples

Download data

(Submitter supplied) Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in 4 day old sterile male F1 hybrids of Drosophila simulans and its sibling species, D. more...

Organism:

Drosophila mauritiana; Drosophila sechellia; Drosophila simulans x Drosophila mauritiana; Drosophila simulans

Type:

Expression profiling by array

Platform:

GPL4022

22 Samples

Download data

(Submitter supplied) Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in F1 hybrid male third instar larvae of Drosophila simulans and its sibling species, D. more...

Organism:

Drosophila sechellia; Drosophila simulans; Drosophila sechellia x Drosophila simulans; Drosophila mauritiana

Type:

Expression profiling by array

Platform:

GPL4022

22 Samples

Download data

(Submitter supplied) Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in F1 hybrid male third instar larvae of Drosophila simulans and its sibling species, D. more...

Organism:

Drosophila mauritiana; Drosophila sechellia; Drosophila simulans; Drosophila simulans x Drosophila mauritiana

Type:

Expression profiling by array

Platform:

GPL4022

22 Samples

Download data

(Submitter supplied) Co-expression of genes that physically cluster together is a common characteristic of eukaryotic transcriptomes. Identifying these groups of co-expressed genes is important to the functional annotation of genomes and understanding the evolutionary fates of the clustered genes. We used microarrays to measure gene expression in seven closely related Drosophila species, to identify domains clusters within a species of Drosophila (D. more...

Organism:

Drosophila sechellia; Drosophila teissieri; Drosophila simulans; Drosophila yakuba; Drosophila santomea; Drosophila melanogaster; Drosophila mauritiana

Type:

Expression profiling by array

Platform:

GPL72

48 Samples

Download data: CEL

(Submitter supplied) d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxicity) in brain tissue. The transcriptomic changes that occur in the brain after d-serine exposure have not been fully explored. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS3643

Platform:

GPL1355

24 Samples

Download data: CEL

Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 6 dose sets

Platform:

GPL1355

Series:

GSE10748

24 Samples

Download data: CEL

(Submitter supplied) PURPOSE. Triamcinolone acetonide (TA) and dexamethasone (DEX) are corticosteroids commonly used for ocular inflammation but both can cause ocular hypertension. We investigated the differential gene expression profile of human trabecular meshwork (TM) cells in response to treatment by TA compared to that by DEX. METHODS. Total RNA was extracted from cultured human TM cells treated with TA or DEX and used for microarray gene expression analysis. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL4564

9 Samples

Download data

(Submitter supplied) A study evaluating the effect of stress resistance selection of Drosophila melanogaster. Abstract Here, we report a detailed analysis of changes in gene expression in Drosophila melanogaster selected for multiple eological relevant environmental stress resistance traits. We analyzed females from three biological replicates from seven selection regimes and one control regime using whole genome gene expression arrays. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Dataset:

GDS2830

Platform:

GPL72

24 Samples

Download data: CEL

Analysis of several lines each selected for resistance to a different environmental stress factor. Results provide insight into the molecular and genetic mechanisms that promote adaptation to environmental stresses.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 8 strain sets

Platform:

GPL72

Series:

GSE6558

24 Samples

Download data: CEL