GEO DataSets

Analysis of insulinoma cells after short-term (2hr) and long-term (16hr) stimulation with cAMP agonist forskolin. Incretin hormone GLP-1 enhances islet cell survival via cAMP pathway induction in beta cells. Results provide insight into mechanisms by which GLP-1 promotes pancreatic islet viability.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 agent, 2 time sets

Platform:

GPL6247

Series:

GSE31736

4 Samples

Download data: CEL, CHP

Analysis of superficial (SZ) and intermediate/deep (IDZ) zones microdissected from articular cartilage and resting (RZ) zone from growth plate cartilage of proximal tibial epiphyses of 10-day old rats. Results provide insight into molecular basis of articular and growth plate cartilage divergence.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 3 tissue sets

Platform:

GPL6247

Series:

GSE54216

12 Samples

Download data: CEL

Analysis of hippocampus from F344 rats fed dietary supplement of cholecalciferol (vitamin D3) at doses of 10,000, 1000 and 100 IU/kg diet for 18 weeks. Results provide insight into molecular mechanisms underlying vitamin D-mediated synaptic function enhancement.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 3 dose sets

Platform:

GPL6247

Series:

GSE61326

26 Samples

Download data: CEL

Analysis of kidney from 8-24 week-old, Nr4a1-deficient (Nr4a1−/−) animals developed on the genetic background of the Fawn-Hooded Hypertensive (FHH) rat. The FHH model is susceptible to kidney injury. Results provide insight into the role of Nr4a1 in the pathogenesis of kidney disease.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 genotype/variation, 3 time sets

Platform:

GPL6247

Series:

GSE54714

18 Samples

Download data: CEL, CHP

Analysis of endothelial cells (ECs) isolated from the ductus arteriosus (DA) and aorta of fetuses and neonates. The DA, a fetal shunt artery between the pulmonary artery and the aorta, closes immediately after birth. Results provide insight into EC involvement in DA-specific morphology and function.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 development stage, 2 tissue sets

Platform:

GPL6247

Series:

GSE40500

12 Samples

Download data: CEL

Analysis of PBMCs from males subjected to left coronary artery ligation to induce large myocardial infarctions (MI). Only animals with large MIs develop LV remodeling and heart failure (HF). Results provide insight into the molecular basis of the progression of LV remodeling and HF.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 3 disease state, 2 protocol sets

Platform:

GPL6247

Series:

GSE47495

11 Samples

Download data: CEL

Analysis of LV from males subjected to left coronary artery ligation to induce large, moderate, or small myocardial infarctions (MI). Only animals with large MIs develop LV remodeling and heart failure (HF). Results provide insight into the molecular basis of the progression of LV remodeling and HF.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 3 disease state, 4 protocol sets

Platform:

GPL6247

Series:

GSE47495

23 Samples

Download data: CEL

Temporal analysis of loaded leg gastrocnemius of females (subjected to neuromuscular blockade, mechanical ventilation) following unilateral passive mechanical loading (PML). Results provide insight into molecular basis of the beneficial effects of PML on muscle mass and function in this ICU model.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 protocol, 3 time sets

Platform:

GPL6247

Series:

GSE37944

46 Samples

Download data: CEL

Analysis of fetal brains following maternal immune activation (MIA) induced by treating pregnant dams with lipopolysaccharide. MIA is a risk factor for the development of schizophrenia and autism. Results provide insight into the effect of MIA on the fetal brain at the molecular level.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 agent sets

Platform:

GPL6247

Series:

GSE34058

19 Samples

Download data: CEL

Analysis of P4 ovaries of Sprague-Dawley females exposed to growth factors. Ovarian primordial follicles are critical for female reproduction and comprise a finite pool of gametes arrested in development. Results provide insight into molecular mechanisms underlying primordial follicle development.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 10 agent sets

Platform:

GPL6247

Series:

GSE20324

44 Samples

Download data: CEL

Analysis of pancreatic islets of control diet (CD)-fed, 13 week old female offspring of high-fat-diet (HFD)-fed Sprague-Dawley males mated with CD-fed females. Results provide insight into molecular mechanisms contributing to Type 2 diabetes-related impairments seen in offspring of obese fathers.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 growth protocol sets

Platform:

GPL6247

Series:

GSE19877

11 Samples

Download data: CEL

Analysis of kidney proximal tubular cells of streptozotocin-induced, type 1 diabetes (T1D) rats treated with C-peptide for 2 hours. Proinsulin C-peptide exerts renoprotective effects in T1D. Results provide insight into molecular mechanisms underlying the protective effects of C-peptide.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL6247

Series:

GSE24687

5 Samples

Download data: CEL