GEO DataSets

Analysis of ecdysone receptor (EcR) depleted animals 4 hours before to 4 hours after the start of pupariation. EcR is part of receptor complex for 20-hydroxyecdysone (20E), a hormone that triggers developmental transitions in insects. Results provide insight into the mechanisms regulated by 20E.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 development stage, 2 protocol, 3 time sets

Platform:

GPL72

Series:

GSE3069

18 Samples

Download data: CEL

Analysis of third instar wing disc from EGFR dominant negative (71B-Gal4; UAS EgfrDN) and EGFR activated (71B-GAL4; UAS EgfrACT) larvae. Aberrant signaling of highly conserved EGFR pathway is implicated in a number of diseases. Results provide insight into the identity of new EGFR-responsive genes.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:

GPL72

Series:

GSE34872

6 Samples

Download data: CEL

Analysis of male and female flies of 5 wild-type laboratory strains. Results provide insight into the extent to which transcriptional variation is inherent in commonly used laboratory strains and the relationship of variation in gene expression to sexual dimorphism.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 2 gender, 5 strain sets

Platform:

GPL72

Series:

GSE9149

29 Samples

Download data: CEL

Analysis of whole bodies of yellow white (y, w) adult female insects topically treated with exogenous juvenile hormone (JH) III. JH can modulate immunity in insects. Results provide insight into the molecular mechanisms underlying JH regulation of innate immunity in insects.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL72

Series:

GSE9001

4 Samples

Download data: CEL, CHP, EXP, TIFF

Analysis of mutant embryos lacking both maternal and zygotic Held out wing (HOW), an RNA-binding protein (RBP) highly expressed in the mesoderm during early embryogenesis. how mutant embryos exhibit aberrant mesoderm spreading. Results provide insight into the role of HOW in mesoderm development.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL72

Series:

GSE7772

4 Samples

Download data: CEL, CHP

Analysis of several lines each selected for resistance to a different environmental stress factor. Results provide insight into the molecular and genetic mechanisms that promote adaptation to environmental stresses.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 8 strain sets

Platform:

GPL72

Series:

GSE6558

24 Samples

Download data: CEL

Analysis of cultured larval organs treated with 20-hydroxyecdysone (20E) alone or in combination with cycloheximide to distinguish primary responses to 20E signal. Organs dissected from third instar larvae. Results provide insight into the molecular events triggered by 20E during insect development.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 4 agent sets

Platform:

GPL72

Series:

GSE3060

12 Samples

Download data: CEL

Analysis of animals before and after pupariation. A pulse of steroid hormone 20-hydroxyecdysone (20E) at late 3rd instar triggers puparium formation; a second 20E pulse after pupariation marks the prepupal-to-pupal transition. Results provide insight into the molecular mechanisms of 20E signaling.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 3 development stage, 9 time sets

Platform:

GPL72

Series:

GSE3057

27 Samples

Download data: CEL

Analysis of p53 mutant embryos exposed to gamma radiation. Within 90 minutes of radiation exposure, apoptosis is observed in embryonic and post-embryonic tissues of wild type but not p53 mutants. Results provide insight into the molecular basis of this p53-dependent apoptogenic response.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 agent, 3 strain sets

Platform:

GPL72

Series:

GSE2780

10 Samples

Download data: CEL, EXP

Analysis of first instar larvae containing a chromosome 4 specific protein POF null mutation. POF is an autosome-specific protein that regulates gene expression in chromosome 4 in its entirety. Results provide insight into the molecular mechanisms that regulate chromosome 4 specific gene expression.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:

GPL72

Series:

GSE5984

7 Samples

Download data: CEL

Analysis of heads of animals overexpressing the RNA-binding protein LARK. Results provide insight into the identity of transcripts regulated by LARK in the neurons of the central nervous system.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL72

Series:

GSE6420

6 Samples

Download data: CEL, EXP

Analysis of the reproductive tracts of females up to 24 hours after mating. Male-derived accessory gland proteins transferred to females during mating affect reproductive physiology. Results provide insight into the response of female reproductive tissues to male-derived molecules and sperm.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 protocol, 5 time sets

Platform:

GPL72

Series:

GSE5012

21 Samples

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Analysis of mRNA purified by mRNA-tagging from photoreceptors cells. These cells are engineered to express a FLAG-tagged poly(A)-binding protein (PABP) that allows separation of their mRNA from those of cells not expressing the tagged PABP. Results provide insight into the validity of this approach.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 genotype/variation, 2 tissue sets

Platform:

GPL72

Series:

GSE1790

14 Samples

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Analysis of heads of transgenics expressing a polyglutamine-expanded neurotoxin in the major timeless (tim)-expressing cells of the adult brain. tim is a clock gene. Results provide insight into the effect of the complete absence of clock-neuron function on behavior and molecular phenotypes.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL72

Series:

GSE2422

6 Samples

Download data: CEL, EXP

Analysis of heads of Canton-S males selected for increased aggressive behavior. Gene expression examined after 21 generations of selection. Results provide insight into the molecular underpinnings of aggressive behavior.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 4 other, 2 strain sets

Platform:

GPL72

Series:

GSE5335

12 Samples

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Analysis of Kc167 cells following gamma-irradiation, ecdysone treatment, or both. Pretreatment of Kc167 cells with ecdysone increases the sensitivity of these cells to gamma-irradiation.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 4 agent sets

Platform:

GPL72

Series:

GSE3072

4 Samples

Download data: CEL, EXP

Analysis of brains of adult Canton S females following mushroom body (MB) ablation with hydroxyurea. MBs are the centers for higher-order functions in arthropod brains. Results provide insight into the molecular mechanisms controlling the development of MBs.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL72

Series:

GSE3379

6 Samples

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Analysis of heat-resistant females at various time points up to 64 hours following short-term heat treatment at 36 degrees C for 1 hour. Results provide insight into the cellular response to heat stress.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 other, 2 stress, 9 time sets

Platform:

GPL72

Series:

GSE5147

36 Samples

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Analysis of testes from bgcn mutants with or without Os ligand overexpression. Testes of bgcn mutants are enriched in transit amplifying cells, while those of Os overexpressing bgcn mutants are enriched in germline and somatic stem cells. Results provide insight into the regulation of stem cells.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 3 genotype/variation sets

Platform:

GPL72

Series:

GSE4188

16 Samples

Download data: CEL

Analysis of early embryos at various stages of development: before zygotic transcription, during the slow and the fast phases of cellularization, and at the beginning and the end of gastrulation. Results provide insight into the molecular mechanisms underlying the control of cellularization.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 5 development stage sets

Platform:

GPL72

Series:

GSE3955

15 Samples

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