GEO DataSets

Analysis of maternal-zygotic (MZ) dicer mutant embryos that lack miR-430 and mutants rescued with miR-430. MZdicer mutants cannot generate mature miRNAs; miR-430 accumulates during maternal-to-zygotic transition and regulates morphogenesis during early development. Results identify miR-430 targets.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 3 development stage, 2 genotype/variation, 2 protocol sets

Platform:

GPL1319

Series:

GSE4201

15 Samples

Download data: CEL, EXP

Analysis of eyes from 24-48 hour post-fertilization embryos exposed to 1.5% ethanol. Ethanol exposure during retinal neurogenesis associated with microphthalmic defects. Results provide insight into molecular mechanisms underlying ethanol exposure-mediated developmental retinal defects.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 2 agent, 5 time sets

Platform:

GPL1319

Series:

GSE51427

9 Samples

Download data: CEL, CHP

Analysis of embryos treated with ethanol in embryo medium from 2 hours post fertilization (hpf) to 8hpf. FASD occurs when pregnant mothers consume alcohol, causing embryonic ethanol exposure and characteristic developmental defects. Results provide insight into molecular basis of FASD pathogenesis.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL1319

Series:

GSE48380

14 Samples

Download data: CEL, CHP

Analysis of brain from young (7.5-8.5 months) and old (31-36 months) wildtype males and females. Brains are sexually dimorphic in adults. Results provide insight into the molecular mechanisms associated with brain aging across gender.

Organism:

Danio rerio

Type:

Expression profiling by array, transformed count, 2 age, 2 gender sets

Platform:

GPL1319

Series:

GSE53430

12 Samples

Download data: CEL

Analysis of pineal gland across 5 developmental stages (3 larval, 2 adult) during the day and night. Pineal gland is a site of melatonin production, contains photoreceptor cells, and acts as a circadian clock pace maker. Results provide insight into the molecular basis of pineal gland development.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 5 age, 2 development stage, 2 time, 2 tissue sets

Platform:

GPL1319

Series:

GSE13371

69 Samples

Download data: CEL

Analysis of Hand2 mutant embryo hearts at 19 hpf. Hand2 is a myocardial transcription factor essential for fusion of bilateral cardiomyocyte populations moving toward the embryonic midline. Results provide insight into downstream components of the Hand2 pathway that mediates cardiac morphogenesis.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL1319

Series:

GSE23381

6 Samples

Download data: CEL

Analysis of wild-type embryos injected with Ovo1 morpholino antisense oligos. At 12 hpf, the Ovo1 morphants begin showing neural crest (NC) defects wherein a subset of NC cells aggregates in the dorsal midline above the neural tube. Results provide insight into the role of Ovo1 in NC migration.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL1319

Series:

GSE21539

6 Samples

Download data: CEL

Analysis of hearts of zebrafish 1 to 7 days following partial heart amputation. Unlike mammals, zebrafish hearts display an extensive regenerative capacity. Results provide insight into the molecular basis of this regenerative capacity.

Organism:

Danio rerio

Type:

Expression profiling by array, transformed count, 2 protocol, 5 time sets

Platform:

GPL1319

Series:

GSE17993

15 Samples

Download data: CEL

Analysis of fog-sk8 mutant embryos containing a severe truncation of Spt5. Spt5 regulates transcription elongation. Results identify Spt5 target genes during development.

Organism:

Danio rerio

Type:

Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:

GPL1319

Series:

GSE12826

6 Samples

Download data: CEL

Analysis of hearts from embryos treated for up to 12 hours with retinoic acid (RA) or 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD). Zebrafish embryos treated with RA or TCDD develop cardiac malformation and heart failure.

Organism:

Danio rerio

Type:

Expression profiling by array, transformed count, 4 agent, 4 time sets

Platform:

GPL1319

Series:

GSE9020

48 Samples

Download data: CEL, EXP

Analysis of ovaries following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) at concentrations of up to 100 parts per billion (ppb). TCDD is a reproductive toxicant and endocrine disruptor in vertebrates. Results provide insight into molecular mechanisms underlying TCDD toxicity.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 4 dose sets

Platform:

GPL1319

Series:

GSE4859

4 Samples

Download data: CEL, EXP

Analysis of ovaries following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) at concentrations of up to 100 parts per billion (ppb). TCDD is a reproductive toxicant and endocrine disruptor in vertebrates. Results provide insight into molecular mechanisms underlying TCDD toxicity.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 4 dose sets

Platform:

GPL1319

Series:

GSE4859

4 Samples

Download data: CEL, EXP

Analysis of microdissected embryonic retinas with or without the retinal pigment epithelium (RPE). The RPE is a thin layer of cells that underlies the neural retina and supports the function and development of photoreceptors. Results provide insight into the development of the RPE.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 2 tissue sets

Platform:

GPL1319

Series:

GSE5048

6 Samples

Download data: CEL, DAT

Analysis of 3 and 5-day egy mutant embryos, which contain a mutation in recycling factor p110. This mutation leads to microcephaly and thymus hypoplasia. U4/U6 snRNPs are disrupted in egy mutants. Results provide insight into the mechanisms underlying these developmental defects.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 2 age, 2 genotype/variation sets

Platform:

GPL1319

Series:

GSE5586

10 Samples

Download data

Analysis of hearts of wild type Tuebingen animals subjected to chronic constant hypoxia.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 2 stress sets

Platform:

GPL1319

Series:

GSE4989

10 Samples

Download data: CEL, EXP

Analysis of trunk and tail muscles of runzel (ruz) mutant embryos at 3.5 days post fertilization (dpf). Ruz mutants carry a mutation in the titin gene resulting in muscle degeneration and embryonic lethality. Results provide insight into the pathogenesis of titin muscular dystrophy.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL1319

Series:

GSE4585

6 Samples

Download data

Analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposed caudal fins at various time points up to 5 days post amputation. TCDD prevents caudal fin regeneration. Results provide insight into the pathways required for fin regeneration and the mechanisms of TCDD toxicity.

Organism:

Danio rerio

Type:

Expression profiling by array, count, 2 agent, 3 time sets

Platform:

GPL1319

Series:

GSE3667

18 Samples

Download data: CEL