GEO DataSet Links for BioProject (Select 195591) - GEO DataSets

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Items: 2

Select item 2000456751.

Transcriptome analysis in host defense during high multiplicity mycobacterial infection

(Submitter supplied) This experiment is to compare the transcription patterns of mouse macrophages (J774A.1) infected with BCG, H37Ra and M. smegmatis under high multiplicity of infection (MOI). Through the global transcriptome profiling study, we define a pathogen specific host gene expression pattern and indicate that SRC likely plays a central role in regulating multiple unique signaling pathways activated by MTB infection. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS5634
Platform:: GPL1261
4 Samples

Download data: CEL, CHP

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Accession:: GSE45675

ID:: 200045675

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 56342.

High multiplicity mycobacterial infections of macrophages in vitro

Analysis of macrophage cell line J774A.1 infected with pathogenic mycobacteria BCG and H37Ra and non-pathogenic M. smegmatis under high multiplicity of infection (MOI = 50). Results provide insight into the molecular response of macrophage host cells to pathogenic and non-pathogenic mycobacteria.