GEO DataSet Links for BioProject (Select 160153) - GEO DataSets

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Items: 2

Select item 2000374581.

Expression data from WT and VAChT KDHOM ventricles

(Submitter supplied) VAChT KDHOM mice have a 70% decrease in the vesicular acetylcholine transporter (VAChT) and this leads to a systemic decrease in ACh release and cardiac dysfunction. We used this microarray to determine whether there were transcriptional alterations in the hearts of mutant mice as a result of this long-term decrease in cholinergic tone.

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS4325
Platform:: GPL6246
6 Samples

Download data: CEL

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Accession:: GSE37458

ID:: 200037458

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 43252.

Vesicular acetylcholine transporter knockdown effect on heart

Analysis of heart from vesicular acetylcholine transporter (VAChT)-deficient C57BL/6 males. The VAChT KD animals have a systemic decrease in ACh release and cardiac dysfunction. Results provide insight into potential molecular changes in the heart induced by decreased cholinergic neurotransmission.