GEO DataSet Links for BioProject (Select 147429) - GEO DataSets

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Items: 2

Select item 2000321251.

Mammary Gland Morphological and Gene Expression Changes Underlying Pregnancy Protection of Breast Cancer Tumorigenesis

(Submitter supplied) Pregnancy has been shown to decrease the risk of mammary carcinogenesis in human rretrospective epidemiological studies. In rodents, pregnancy prior to carcinogen administration or after carcinogen challenge has also been shown to reduce the incidence of palpable carcinomas. In this study our objective to determine the underlying genomic signature of the pregnancy and reproductive hormones on the mammary gland that contribute to the protection against mammary gland carcinogenesis. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS4081
Platform:: GPL1355
15 Samples

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Accession:: GSE32125

ID:: 200032125

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 40812.

Effect of full-term pregnancy or hormone treatment on inguinal left mammary gland

Analysis of mammary gland of metestrus Lewis females randomly assigned to 3 groups: control, pregnancy, or hormone (exogenous estrogen and progesterone). Full-term pregnancy or treatment with hormone reduces breast cancer risk. Results provide insight into molecular basis of the protective effect.