GEO DataSet Links for BioProject (Select 146161) - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Links from BioProject

Items: 2

Select item 2000309621.

Primary and secondary CD8 T cells during acute and chronic LCMV infection

(Submitter supplied) Understanding the response of memory CD8 T cells to persistent antigen re-stimulation and the role of CD4 T cell help is critical to the design of successful vaccines for chronic diseases. However, studies comparing the protective abilities and qualities of memory and naïve cells have been mostly performed in acute infections, and little is known about their roles during chronic infections. Herein, we show that memory cells dominate over naïve cells and are protective when present in large enough numbers to quickly reduce infection. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS4555
Platform:: GPL1261
16 Samples

Download data: CEL

Series

Accession:: GSE30962

ID:: 200030962

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 45552.

Lymphocytic choriomeningitis virus infection model during chronic and acute infection: splenic effector CD8 T cell types

Analysis of primary effector (naive) and secondary effector (memory) CD8+ T cells at day 8 post-acute or post-chronic LCMV infection. Results provide insight into the response of memory CD8+ T cells to persistent antigen restimulation, in support of rational vaccine design for chronic infections.