GEO DataSet Links for BioProject (Select 140101) - GEO DataSets

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Items: 2

Select item 2000293761.

Endothelial Cells Express a Unique Transcriptional Profile under Very High Wall Shear Stress Known to Induce Expansive Arterial Remodeling

(Submitter supplied) Chronic high flow can induce arterial remodeling, and this effect is mediated by endothelial cells (ECs) responding to wall shear stress (WSS). To assess how WSS above physiological normal levels affects ECs, we used DNA microarrays to profile EC gene expression under various flow conditions. Cultured bovine aortic ECs were exposed to no flow (0 Pa), normal WSS (2 Pa) and very high WSS (10 Pa) for 24 hrs. more...

Organism:: Bos taurus

Type:: Expression profiling by array

Dataset:: GDS4525
Platform:: GPL2112
9 Samples

Download data: CEL

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Accession:: GSE29376

ID:: 200029376

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 45252.

Aortic endothelial cell response to very high wall shear stress

Analysis of aortic endothelial cells (EC) exposed to high wall shear stress (WSS) for 24hr in an in vitro flow loop system. High WSS often induces expansive remodeling of the artery. Results provide insight into the molecular mechanisms underlying adaptive remodeling under high WSS conditions.