GEO DataSet Links for BioProject (Select 126499) - GEO DataSets

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Items: 2

Select item 2000212311.

Gene expression changes associated with resistance to intravenous corticosteroid therapy in children with severe ulcerative colitis

(Submitter supplied) Although corticosteroids remain a mainstay of therapy for UC, a meta-regression of cohort studies in acute severe ulcerative colitis (UC) showed that 29% of patients fail corticosteroid therapy and require escalation of medical management or colectomy. We aimed to determine whether genes expressed in whole blood early following initiation of intravenous corticosteroid treatment can be associated with response.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4270
Platform:: GPL6244
40 Samples

Download data: CEL

Series

Accession:: GSE21231

ID:: 200021231

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 42702.

Intravenous corticosteroid therapy effect on children with severe ulcerative colitis: peripheral blood

Analysis of peripheral blood from pediatric patients with severe ulcerative colitis (UC) on day 3 of intravenous corticosteroid (IVCS) therapy. Individual response to IVCS is variable. Results provide insight into the molecular mechanisms underlying response to IVCS in pediatric UC.