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Candida albicans pathways that protect against organic peroxides and lipid peroxidation.

(Submitter supplied) Human fungal pathogens must survive diverse reactive oxygen species (ROS) produced by host immune cells. ROS can oxidize a range of cellular molecules including proteins, lipids, and DNA. Formation of lipid radicals by ROS can be especially damaging, as it leads to a chain reaction of lipid peroxidation that causes widespread damage to the plasma membrane. Most previous studies on antioxidant pathways in fungal pathogens have been conducted with hydrogen peroxide, so the pathways used to combat organic peroxides and lipid peroxidation are not well understood. more...
Organism:
Candida albicans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24129
9 Samples
Download data: CSV
Series
Accession:
GSE275502
ID:
200275502

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