GEO DataSet Links for BioProject (Select 107355) - GEO DataSets

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Items: 2

Select item 2000108561.

Expression data from decoy receptor 3-treated monocyte-derived macrophages

(Submitter supplied) Decoy receptor 3 (DcR3) is a member of the TNF receptor superfamily and is up-regulated in tumors that originate from a diversity of lineages. DcR3 is capable of promoting angiogenesis, inducing dendritic cell apoptosis, and modulating macrophage differentiation. Since tumor-associated macrophages (TAMs) are the major infiltrating leukocytes in most malignant tumors, we used microarray technology to investigate whether DcR3 contributes to the development of TAMs. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3258
Platform:: GPL570
4 Samples

Download data: CEL

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Accession:: GSE10856

ID:: 200010856

Select item 32582.

Monocyte-derived macrophage response to decoy receptor 3

Analysis of monocyte-derived macrophages (MDMs) treated with decoy receptor 3 (DcR3) recombinant fusion protein. DcR3, a TNF receptor superfamily member, is up-regulated in tumors from diverse lineages. Results provide insight into the role of DcR3 in tumor-associated macrophage (TAM) development.