GEO DataSets

(Submitter supplied) Bacillus anthracis causes anthrax infections in mammals. Large-scale mortality resulting from the intentional release of B. anthracis spores represents a potential bioterrorism threat. Inhalational anthrax almost invariably proceeds to fatal systemic infection, characterized by massive bacteremia. A better understanding of host-pathogen interactions is urgently needed for effective treatment of this lethal disease. more...

Organism:

Bacillus anthracis; Bacillus anthracis str. Sterne

Type:

Expression profiling by array

Platform:

GPL23273

4 Samples

Download data: MEV

(Submitter supplied) Investigation of whole genome expression level changes in Bacillus anthracis Sterne deltaClpX mutant compared to the wild-type strain after growth in nutrient rich media. The deltaClpX mutant used in this study is described in McGillivray et al. 2009. ClpX Protease Contributes to Antimicrobial Peptide Resistance and Virulence Phenotypes of Bacillus anthracis. Journal of Innate Immunity 1(5): 494-506.

Organism:

Bacillus anthracis str. Sterne

Type:

Expression profiling by array

Platform:

GPL23020

6 Samples

Download data: TXT, XLSX

(Submitter supplied) Subinhibitory concentrations of compound used to assess their influence on the gene expression profile of Bacillus anthracis.

Organism:

Bacillus anthracis str. Sterne

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20947

9 Samples

Download data: TXT

(Submitter supplied) Using RNA-seq, we report here that CodY regulation is hierarchically regulated in response to environmental starvation.

Organism:

Bacillus anthracis str. Sterne

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20947

24 Samples

Download data: TXT

(Submitter supplied) The goal of this study is the discovery of (a) meaningful phylogenomic relationships among members of this B. cereus/B. anthracis group, and (b) reliable gene-phenotype associations, e.g. recognition of links between genomic traits and the ability of certain strains to cause various forms of disease. We also tried to elucidate genome evolution aspects that may lead to the emergence of variants that are capable (or have the potential) of causing anthrax-like disease. more...

Organism:

Bacillus anthracis str. Sterne; Bacillus anthracis; Bacillus cereus G9842; Bacillus cereus

Type:

Genome variation profiling by array

Platforms:

GPL9098 GPL9095

315 Samples

Download data: MEV

(Submitter supplied) The goal of this project was to screen soil samples for bacteria that may harbor B. anthracis virulence-associated genes (VAGs). There is currently no information about the prevalence of these types of organisms in the environment. Due to increased environmental monitoring of select agents by programs such as BioWatch and biodetection systems in place at the United States Post Offices and Department of State locations, it has become critical that we not only better understand the natural range of B. more...

Organism:

Bacillus anthracis; Bacillus cereus; Bacillus anthracis str. Sterne

Type:

Genome variation profiling by array

Platforms:

GPL9098 GPL9095

202 Samples

Download data: MEV

(Submitter supplied) High density DNA array NimbleGen design name 2006-07-27_TI260799_60mer represents 5287 chromosomal genes from Bacillus anthracis Sterne with eighteen 60-mer probe pairs per gene. Each probe is replicated 4 times. The design includes random GC and other control probes. The Platform data table reflects a condensed representation of the expression array's replicate (SEQ_ID) features. The .ndf and .ngd files are linked below as supplementary files. more...

Organism:

Bacillus anthracis str. Sterne

1 Series

6 Samples

Download data: NDF, NGD