GSM958832[Accession] - GEO DataSets

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Items: 4

Select item 2000392521.

Expression changes in Caenorhabditis elegans xpa-1 mutant

(Submitter supplied) Background: The ability of an organism to repair DNA damage is implicated in carcinogenesis and aging. Interestingly expression profiling of Nucleotide Excision Repair (NER) deficient segmental progeroid mice revealed gene expression changes resembling these observed in aged wild type animals. Our previous transcriptional profiling of NER-deficient C. elegans xpa-1 mutant showed overrepresentation of genes involved in lifespan determination and upregulation of several oxidative stress response genes (Fensgard et al. more...

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array

Dataset:: GDS4564
Platform:: GPL200
10 Samples

Download data: CEL

Series

Accession:: GSE39252

ID:: 200039252

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 45642.

Nucleotide excision repair mutant xpa-1

Analysis of xpa-1 mutants deficient in nucleotide excision repair (NER). Transcription-blocking DNA damage is believed to contribute to aging and underlie activation of oxidative stress responses (OSR). Results provide insight into the transcriptomic reprogramming response in xpa-1 mutants.

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:: GPL200
Series:: GSE39252
10 Samples

Download data: CEL

DataSet

Accession:: GDS4564

ID:: 4564

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000002003.

[Celegans] Affymetrix C. elegans Genome Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Has 22625 entries and was indexed 30-Apr-2002. Sequence information used for the design of the C. elegans array was downloaded from the Sanger Center database on December 05, 2000 and from GenBank release 121. All sequences were functionally reannotated by Affymetrix for improved descriptions. more...