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(Submitter supplied) Persons with Down syndrome (DS) exhibit low muscle strength that significantly impairs their physical functioning. The Ts65Dn mouse model of DS also exhibits muscle weakness in vivo and may serve as a useful model to examine potential factors responsible for DS-associated muscle dysfunction. Therefore, the purpose of this experiment was to directly assess skeletal muscle function in the Ts65Dn mouse and to reveal potential mechanisms of DS-associated muscle weakness. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS4376

Platform:

GPL6246

8 Samples

Download data: CEL, CHP

Analysis of soleus muscle, in the basal state, from five-month-old Ts65Dn Down syndrome (DS) males. Ts65Dn DS model exhibits muscle weakness in vivo. Results provide insight into the molecular mechanisms underlying DS-associated muscle dysfunction.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 strain sets

Platform:

GPL6246

Series:

GSE39159

8 Samples

Download data: CEL, CHP

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site

Organism:

Mus musculus

143 DataSets

2504 Series

28 Related Platforms

30419 Samples

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