GSM886427[Accession] - GEO DataSets

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Items: 4

Select item 2000362871.

Expression data from primary human keratinocytes exposed to cytokines in vitro (IL-4, IL-13, IL-17A, IFN-alpha, IFN-gamma, TNF)

(Submitter supplied) The clinical features of psoriasis, characterized by sharply demarcated scaly erythematous plaques, are typically so distinctive that a diagnosis can easily be made on these grounds alone. However, there is great variability in treatment response between individual patients, and this may reflect heterogeneity of inflammatory networks driving the disease. In this study, whole-genome transcriptional profiling was used to characterize inflammatory and cytokine networks in 62 lesional skin samples obtained from patients with stable chronic plaque psoriasis. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4601
Platform:: GPL570
24 Samples

Download data: CEL

Series

Accession:: GSE36287

ID:: 200036287

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 46012.

Primary keratinocyte response to in vitro cytokine exposure

Analysis of cultured keratinocytes treated with various cytokines: interleukin-4, -13, -17A, interferon-α, -γ, or TNF. Marked proliferation of keratinocytes characterizes the chronic inflammatory skin disease psoriasis. Results provide insight into cytokine activity signatures in keratinocytes.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 7 agent, 4 individual sets

Platform:: GPL570
Series:: GSE36287
24 Samples

Download data: CEL

DataSet

Accession:: GDS4601

ID:: 4601

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...