GSM857360[Accession] - GEO DataSets

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Items: 4

Select item 2000349211.

NANOG-OCT4-SOX2 Regulatory Module in Human Embryonic Stem Cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
69 Samples

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Series

Accession:: GSE34921

ID:: 200034921

Select item 2000349042.

NANOG-OCT4-SOX2 Regulatory Module in Human Embryonic Stem Cells (dataset 1)

(Submitter supplied) The transcription factors Nanog, Oct4 and Sox2 are the master regulators of pluripotency in mouse embryonic stem cells (mESCs), however, their functions in human ESCs (hESCs) have not been rigorously defined. Here we show that the requirements for NANOG, OCT4 and SOX2 in hESCs differ from those in mESCs. Both NANOG and OCT4 are required for self-renewal and repress differentiation. OCT4 controls both extraembryonic and epiblast-derived cell fates in a BMP4-dependent manner. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
40 Samples

Download data: TXT

Series

Accession:: GSE34904

ID:: 200034904

Select item 1000105583.

Illumina HumanHT-12 V4.0 expression beadchip

(Submitter supplied) The HumanHT-12 v4 Expression BeadChip provides high throughput processing of 12 samples per BeadChip without the need for expensive, specialized automation. The BeadChip is designed to support flexible usage across a wide-spectrum of experiments. The updated content on the HumanHT-12 v4 Expression BeadChips provides more biologically meaningful results through genome-wide transcriptional coverage of well-characterized genes, gene candidates, and splice variants. more...