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Items: 5

1.

IMI MARCAR Project: towards novel biomarkers for cancer risk assessment

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens; Rattus norvegicus; synthetic construct
Type:
Expression profiling by array; Non-coding RNA profiling by array; Methylation profiling by genome tiling array
14 related Platforms
2666 Samples
Download data: CEL, CSV, PAIR, TXT
Series
Accession:
GSE68387
ID:
200068387
2.

Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Methylation profiling by genome tiling array; Expression profiling by array
Platforms:
GPL7060 GPL1261
120 Samples
Download data: CEL, PAIR
Series
Accession:
GSE34463
ID:
200034463
3.

Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice [MeDIP array].

(Submitter supplied) Evidence suggests that epigenetic perturbations are involved in the adverse effects associated with some drugs and toxicants, including certain classes of non-genotoxic carcinogens. Such epigenetic changes (altered DNA methylation and covalent histone modifications) may take place at the earliest stages of carcinogenesis and their identification holds great promise for biomedical research. Here, we evaluate the sensitivity and specificity of genome-wide epigenomic and transcriptomic profiling in phenobarbital (PB)-treated B6C3F1 mice, a well-characterized rodent model of non-genotoxic liver carcinogenesis. more...
Organism:
Mus musculus
Type:
Methylation profiling by genome tiling array
Platform:
GPL7060
80 Samples
Download data: PAIR
Series
Accession:
GSE34462
ID:
200034462
4.

NimbleGen MM8 Mouse Promoter plus CpG Island 374K Tiling Array

(Submitter supplied) Source: UCSC Build: MM8 Probe Length: 50-75mer Promoter Upstream Tiling (bp): 1300 Promoter Downstream Tiling (bp): 500 Protocol: See www.nimblegen.com
Organism:
Mus musculus
9 Series
119 Samples
Download data: NDF, POS
Platform
Accession:
GPL7060
ID:
100007060
5.

Liver_Control_10_rep2

Organism:
Mus musculus
Source name:
Liver_Control_10_MeDIP (channel 1) Liver_Control_10_Input DNA (channel 2)
Platform:
GPL7060
Series:
GSE34462 GSE34463 GSE68387
Download data: PAIR
Sample
Accession:
GSM849557
ID:
300849557
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