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Items: 5

1.

IMI MARCAR Project: towards novel biomarkers for cancer risk assessment

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens; Rattus norvegicus; synthetic construct
Type:
Expression profiling by array; Non-coding RNA profiling by array; Methylation profiling by genome tiling array
14 related Platforms
2666 Samples
Download data: CEL, CSV, PAIR, TXT
Series
Accession:
GSE68387
ID:
200068387
2.

Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Methylation profiling by genome tiling array; Expression profiling by array
Platforms:
GPL7060 GPL1261
120 Samples
Download data: CEL, PAIR
Series
Accession:
GSE34463
ID:
200034463
3.

Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice [Expression array].

(Submitter supplied) Evidence suggests that epigenetic perturbations are involved in the adverse effects associated with some drugs and toxicants, including certain classes of non-genotoxic carcinogens. Such epigenetic changes (altered DNA methylation and covalent histone modifications) may take place at the earliest stages of carcinogenesis and their identification holds great promise for biomedical research. Here, we evaluate the sensitivity and specificity of genome-wide epigenomic and transcriptomic profiling in phenobarbital (PB)-treated B6C3F1 mice, a well-characterized rodent model of non-genotoxic liver carcinogenesis. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
40 Samples
Download data: CEL
Series
Accession:
GSE34423
ID:
200034423
4.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4546 Series
40 Related Platforms
58941 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
5.

PB_Kidney_treated_20

Organism:
Mus musculus
Source name:
4 wk_Phenobarbital treatment_kidney
Platform:
GPL1261
Series:
GSE34423 GSE34463 GSE68387
Download data: CEL
Sample
Accession:
GSM848838
ID:
300848838
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