GEO DataSets

(Submitter supplied) Although HSF1 is known to play an important role in regulating the cellular response to proteotoxic stressors, little is known about the structure and function of the HSF1 signaling network under both stressed and unstressed conditions. In this study, we used a combination of chromatin immunoprecipitation (ChIP) microarray analysis and time course gene expression microarray analysis with and without siRNA-mediated inhibition of HSF1 comprehensively identify genes directly and indirectly regulated by HSF1 and examine the structure of the extended HSF1 signaling network. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS1733

Platform:

GPL571

42 Samples

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Analysis of HSF1-depleted HeLa cells at various time points up to 24 hours following heat shock treatment at 43 degrees C. Heat shock transcription factor HSF1 silenced using RNA interference (siHSF1_1, siHSF1_2). Results provide insight into the structure and function of the HSF1 signaling network.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 agent, 2 protocol, 6 time sets

Platform:

GPL571

Series:

GSE3697

42 Samples

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(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...

Organism:

Homo sapiens

84 DataSets

641 Series

12 Related Platforms

24467 Samples

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