GSM845241[Accession] - GEO DataSets

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Items: 4

Select item 2000278441.

Enhancer Decommissioning by LSD1 During Embryonic Stem Cell Differentiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL9250 GPL13112 GPL4134
28 Samples

Download data: TXT, WIG, YLF

Series

Accession:: GSE27844

ID:: 200027844

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000278412.

Enhancer Decommissioning by LSD1 During Embryonic Stem Cell Differentiation (ChIP-seq)

(Submitter supplied) Transcription factors and chromatin modifiers play important roles in programming and reprogramming of cellular states during development. Much is known about the role of these regulators in gene activation, but relatively little is known about the critical process of enhancer silencing during differentiation. Here we show that the H3K4/K9 histone demethylase LSD1 plays an essential role in decommissioning enhancers during differentiation of embryonic stem cells (ESCs). more...