GSM830931[Accession] - GEO DataSets

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Items: 4

Select item 2000336061.

Gene expression changes in human hepatocytes exposed to VX (O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothiolate)

(Submitter supplied) Organophosphorus compounds induce hepatotoxicity through currently unknown mechanisms, which need to be unraveled by a comprehensive and systematic approach such as genome-wide gene expression analysis. We used microarrays to study gene expression changes in human hepatocytes after exposure to VX, and identified pathways underlying these changes.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3998
Platform:: GPL570
15 Samples

Download data: CEL

Series

Accession:: GSE33606

ID:: 200033606

Analyze with GEO2R

Select item 39982.

Organophosphorus compound VX effect on hepatocytes: dose response

Analysis of hNHEPS hepatocytes exposed to sublethal concentrations (up to 10μM) of the highly toxic organophosphorus (OP) compound VX (O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothiolate). Results provide insight into molecular mechanisms underlying OP-induced hepatotoxicity.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent, 3 dose, 2 time sets

Platform:: GPL570
Series:: GSE33606
15 Samples

Download data: CEL

DataSet

Accession:: GDS3998

ID:: 3998

GEO Profiles Analyze DataSet

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...