GSM805424[Accession] - GEO DataSets

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Items: 4

Select item 2000325211.

Toxicogenomic responses of C. elegans to gold nanoparticles

(Submitter supplied) We used Au nanoparticles (Au-NPs) as a model for studying particle specific effects of manufactured nanomaterials (MNMs) by examining the toxicogenomic responses in a model soil organism, free living nematode Caenorhabditis elegans. Global genome expression for nematodes exposed to 4-nm citrate-coated Au-NPs at the LC10 (5.9 mg L-1) revealed significant differential expression of 797 genes. The levels of expression for five genes (apl-1, dyn-1, act-5, abu-11, and hsp-4) were confirmed independently with qRT-PCR. more...

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array

Dataset:: GDS4571
Platform:: GPL200
6 Samples

Download data: CEL

Series

Accession:: GSE32521

ID:: 200032521

Select item 45712.

Toxicogenomic response to gold nanoparticle exposure

Analysis of age-synchronized L3 nematodes exposed to LC10 of gold nanoparticles (Au-NPs). The Au-NPs are used as a model for studying particle-specific effects of manufactured nanomaterials (MNMs). Results provide insight into in vivo particle-specific toxicity of Au-NPs to C. elegans.

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array, transformed count, 2 agent sets

Platform:: GPL200
Series:: GSE32521
6 Samples

Download data: CEL

DataSet

Accession:: GDS4571

ID:: 4571

Select item 1000002003.

[Celegans] Affymetrix C. elegans Genome Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Has 22625 entries and was indexed 30-Apr-2002. Sequence information used for the design of the C. elegans array was downloaded from the Sanger Center database on December 05, 2000 and from GenBank release 121. All sequences were functionally reannotated by Affymetrix for improved descriptions. more...