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Items: 3

1.

Single-cell RNA-sequencing of human spleens reveals an IDO-1+ Tolerogenic Dendritic Cell subset in pancreatic cancer patients that is absent in normal individuals.

(Submitter supplied) Local and systemic immunosuppression are prominent features of pancreatic cancer, rendering anti-tumor effector cells inactive and immunotherapeutic approaches ineffective. The spleen, an understudied point of antigen-presentation and T cell priming in humans, holds particular importance in pancreatic cancer due to its proximity to the developing tumor. As main effectors of antigen presentation, dendritic cells display antigens to lymphocytes, thereby bridging the innate and adaptive immune response. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21697
7 Samples
Download data: MTX, TSV
Series
Accession:
GSE247635
ID:
200247635

2.

NextSeq 550 (Homo sapiens)

Organism:
Homo sapiens
1500 Series
44597 Samples
Download data
Platform
Accession:
GPL21697
ID:
100021697

3.

spleen, PDAC_62, scRNAseq

Organism:
Homo sapiens
Source name:
Spleen PDAC
Platform:
GPL21697
Series:
GSE247635
Download data: MTX, TSV
Sample
Accession:
GSM7898201
ID:
307898201

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db=gds|term=GSM7898201[Accession]|query=1|qty=2|blobid=MCID_674c341196d9ad0406217c06|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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