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Items: 3

1.

Molecular mechanisms of BCAT1 in ASK120067-resistant NSCLC cells

(Submitter supplied) To investigate the mechanism of BCAT1 in mediating resistance to third-generation EGFR-TKI, we employed RNA-seq analysis to compare the transcriptome signature of ASK120067-resistant NSCLC cells with or without BCAT1 knockdown. Here, gene set enrichment (GSEA) revealed a significant decrease in the expression of genes in glycolysis pathway following small interfering RNA (siRNA)-mediated BCAT1 knockdown, which indicated the role for BCAT1 in supporting TKI resistance through upregulation of glycolysis.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
6 Samples
Download data: TXT
Series
Accession:
GSE247584
ID:
200247584

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
17299 Series
937865 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

siBCAT1_2

Organism:
Homo sapiens
Source name:
Lung adenocarcinoma
Platform:
GPL24676
Series:
GSE247584
Download data
Sample
Accession:
GSM7893359
ID:
307893359

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db=gds|term=GSM7893359[Accession]|query=1|qty=2|blobid=MCID_674a1b600b8f33053005ec89|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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