GSM7871365[Accession] - GEO DataSets

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Items: 4

Select item 2002465611.

Methylomic signatures of tau and beta amyloid in transgenic mouse models of Alzheimer’s disease neuropathology

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus; Rattus norvegicus

Type:: Methylation profiling by array; Methylation profiling by high throughput sequencing

Platforms:: GPL17021 GPL28271
283 Samples

Download data: IDAT

Series

Accession:: GSE246561

ID:: 200246561

Analyze with GEO2R

Select item 2002465592.

Methylomic signatures of tau and beta amyloid in transgenic mouse models of Alzheimer’s disease neuropathology [HorvathMammalMethylChip40 Methylation Beadchip]

(Submitter supplied) We identified widespread DNA methylation changes associated with the development of both tau and amyloid neuropathology, including differentially methylated positions (DMPs) and regions (DMRs) at loci previously implicated in AD and overlapping changes identified in our ongoing analyses of human post-mortem AD brains.

Organism:: Homo sapiens; Rattus norvegicus; Mus musculus

Type:: Methylation profiling by array

Platform:: GPL28271
159 Samples

Download data: CSV, IDAT

Series

Accession:: GSE246559

ID:: 200246559

Analyze with GEO2R

Select item 1000282713.

Illumina HorvathMammalianMethylChip40 BeadChip

(Submitter supplied) Developed in the labs of Steve Horvath and Jason Ernst. The mammalian array platform applies to ALL mammals (humans, mouse, rat, sheep, horses, pigs, etc.). The array design is similar to the Illumina Infinium 450K array but it contains fewer up to 37492 CpGs. Additional material can be found on the Github page https://github.com/shorvath/MammalianMethylationConsortium/ A vignette on using the mammal methylation array with SeSAMe is available from https://bioconductor.org/packages/release/bioc/vignettes/sesame/inst/doc/mammal.html. more...