GSM783303[Accession] - GEO DataSets

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Items: 4

Select item 2000315611.

Transcriptional analysis of organ-specific toxicity induced by a panPPAR agonist in mice: Identification of organ-specific toxicity biomarkers

(Submitter supplied) In this study, we aim to identify candidate biomarkers which may be useful as surrogate indicators of toxicity for pre-clinical development of panPPAR-agonist drug candidates. Gene expression microarray, histopathology and clinical chemistry data were generated from liver, heart, kidney and skeletal muscles of three groups of mice administered with three different dosages of an experimental pan-peroxisome proliferator-activated receptor (pan-PPAR) agonist, PPM-201, for 14 days. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS4806
Platform:: GPL1261
36 Samples

Download data: CEL

Series

Accession:: GSE31561

ID:: 200031561

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 48062.

Pan-peroxisome proliferator-activated receptor agonist effect on various tissues: dose response

Analysis of liver, heart, kidney and skeletal muscle from animals treated with different doses (therapeutic, toxic) of PPM-201, a pan-peroxisome proliferator-activated receptor (pan-PPAR) agonist. Results provide insight into molecular bases of organ-specific toxicity induced by a panPPAR agonist.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 agent, 3 dose, 4 tissue sets

Platform:: GPL1261
Series:: GSE31561
36 Samples

Download data: CEL

DataSet

Accession:: GDS4806

ID:: 4806

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000012613.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...