GSM775302[Accession] - GEO DataSets

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Items: 4

Select item 2000312801.

Transcript level in F9 teratocarcinoma WT and RARalpha knockout in presence and absence of all-trans retinoic acid

(Submitter supplied) Retinoic acid receptors (RARs) α, β and γ are key regulators of embryonic development. Hematopoietic differentiation is regulated by RARα, and several types of leukemia show aberrant RARα activity. We demonstrate that RARα plays an important role in cellular memory and imprinting by regulating the CpG methylation status of specific promoter regions. We used microarrays to identify genes, which display differential expression in F9 RARalpha knockout (RARaKO) cells relative to F9 wt cells.

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS4294
Platform:: GPL1261
12 Samples

Download data: CEL

Series

Accession:: GSE31280

ID:: 200031280

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 42942.

All-trans retinoic acid effect on retinoic acid receptor α-deficient F9 teratocarcinoma cells

Analysis of F9 teratocarcinoma cells depleted of retinoic acid receptor (RAR)α and treated with all trans retinoic acid (atRA) in the presence of cycloheximide. RARα translocation events are associated with acute promyelocytic leukemia (APL). Results provide insight into the role of RARα in APL.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE31280
12 Samples

Download data: CEL

DataSet

Accession:: GDS4294

ID:: 4294

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000012613.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...