GSM738105[Accession] - GEO DataSets

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Items: 3

Select item 2000297671.

Gene expression profiles in the hippocampi and prefrontal cortex of Df16(A)+/- mice at embryonic day 17, postnatal day 6, and adult stages

(Submitter supplied) Df16(A)+/- mice line is a model of human 22q11 microdeletion syndrome. We conducted an unbiased evaluation of the transcriptional difference in the prefrontal cortex and hippocampus areas between mutant and wild type animals at two early developmental stages (embryonic day 17 and postnatal day 6). These mice were generated by chromosomal engineering and carry a microdeltion of ~1.3Mb in the mouse locus syntenic to the human 22q11.1 The reasoning behind this expression profiling is that consistent alterations in transcriptional programs reflect either downstream (immediate or remote) effects of the deficiency or reactive (compensatory) changes, and can thus point to affected biological processes and molecular functions. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11180
127 Samples

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Accession:: GSE29767

ID:: 200029767

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000111802.

[HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Protocol: see manufacturer's web site