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Items: 4

1.

The time-course transcriptomic responses of THP-1 human macrophage-like cells to W-Beijing Mycobacterium tuberculosis strains of different sublineages

(Submitter supplied) The W-Beijing family of Mycobacterium tuberculosis (Mtb) strains is known for its high-prevalence and -virulence, as well as for its genetic diversity, as recently reported by our laboratories and others. However, little is known about how the immune system responds to these strains. To explore this issue, here we used reverse engineering and genome-wide expression profiling of human macrophage-like THP-1 cells infected by different Mtb strains of the W-Beijing family, as well as by the reference laboratory strain H37Rv. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4258
Platform:
GPL570
40 Samples
Download data: CEL
Series
Accession:
GSE29628
ID:
200029628
2.
Full record GDS4258

THP-1 macrophage-like cells response to W-Beijing Mycobacterium tuberculosis strains: time course

Temporal analysis of macrophage-like THP-1 cell line infected by Mycobacterium tuberculosis (Mtb) W-Beijing strains and H37Rv. Mtb W-Beijing sublineages are highly virulent, prevalent and genetically diverse. Results provide insight into host macrophage immune response to Mtb W-Beijing strains.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 infection, 13 strain, 4 time sets
Platform:
GPL570
Series:
GSE29628
40 Samples
Download data: CEL
3.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...
Organism:
Homo sapiens
602 DataSets
5671 Series
61 Related Platforms
175585 Samples
Download data
Platform
Accession:
GPL570
ID:
100000570
4.

THP1-cells infected by R17.1 strains at 18h

Organism:
Homo sapiens
Source name:
THP1-cells infected by R17.1 strains at 18h
Platform:
GPL570
Series:
GSE29628
Dataset:
GDS4258
Download data: CEL
Sample
Accession:
GSM734305
ID:
300734305
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