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Items: 3

1.

NFKBIE-mutated CLL cells reshape the immune microenvironment and display selective resistance to BTK inhibitor treatment

(Submitter supplied) Inactivating mutations in the NF-kB inhibitor NFKBIE are frequent in chronic lymphocytic leukemia (CLL) and have been associated with accelerated disease progression and inferior responses to chemotherapy. To further understand the role of NFKBIE mutations in CLL, we disrupted by CRISPR/Cas9 editing the NFKBIE gene in CLL cells derived from the Eμ-TCL1 transgenic mouse model and investigated how this will affect CLL growth and response to B cell receptor inhibitor treatment. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
22 Samples
Download data: TXT
Series
Accession:
GSE231799
ID:
200231799

PubMed Full text in PMC Similar studies

2.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
14540 Series
700496 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

3.

NFKBIE_vitro_rep1

Organism:
Mus musculus
Source name:
NFKBIE-ko TCL1-355 TKO cells
Platform:
GPL24247
Series:
GSE231799
Download data
Sample
Accession:
GSM7300705
ID:
307300705

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db=gds|term=GSM7300705[Accession]|query=1|qty=2|blobid=MCID_674c25f9d8260840384c1ade|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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