GEO DataSets

(Submitter supplied) Investigating the molecular basis and correlates of anxiety-related and depression-like behaviors, we generated a mouse model consisting of high (HAB) and low (LAB) anxiety-related behavior mice. We utilized the elevated plus-maze for testing the genetic predisposition to anxiety-related behavior and, consequently, used this as selection criterion for the inbreeding of our animals. In depression-related tests, HAB mice display a more passive, depression-like coping strategy than LAB mice, resembling clinical comorbidity of anxiety and depression as observed in psychiatric patients. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL7467

70 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS4001 GDS4002

Platforms:

GPL6481 GPL7467

148 Samples

Download data: TXT

Analysis of seven brain regions closely connected to the emotion-regulating parts of the limbic system, isolated by micropunching from CD-1 males selectively bred for high (HAB) or low (LAB) anxiety-related behavior. Results provide insight into the molecular mechanisms underlying anxiety.

Organism:

Mus musculus

Type:

Expression profiling by array, log2 ratio, 7 tissue sets

Platform:

GPL7467

Series:

GSE29015

70 Samples

Download data: TXT

(Submitter supplied) The cDNA microarray contains 24192 PCR products derived from different mouse cDNA libraries (sources: Research Genetics, RZPD Deutsches Ressourcenzentrum für Genomforschung, proprietary clones) representing 12387 different unigene clusters (unigene build #143). The spotting buffer contained 3 x SSC and 1.5 M betaine. The PCR products were spotted on GAPS II slides (Corning) using a Chipwriter Pro spotting robot (Biorad) and 48 SMP3 stealth pins (Telechem). more...

Organism:

Mus musculus

1 DataSet

5 Series

160 Samples

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