GSM7110229[Accession] - GEO DataSets

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Items: 4

Select item 2002278841.

Protein-intrinsic properties and context-dependent effects regulate pioneer-factor binding and function

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Drosophila melanogaster

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL21306 GPL19132 GPL25244
190 Samples

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Accession:: GSE227884

ID:: 200227884

PubMed Full text in PMC Similar studies

Select item 2002278822.

Protein-intrinsic properties and context-dependent effects regulate pioneer-factor binding and function [ChIP-Seq]

(Submitter supplied) While chromatin presents a barrier to the binding of many transcription factors, pioneer factors access nucleosomal targets and promote chromatin opening. Despite binding to target motifs in closed chromatin, many pioneer factors display cell-type specific binding and activity. The mechanisms governing pioneer-factor occupancy and the relationship between chromatin occupancy and opening remain unclear. more...