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Items: 3

1.

Exon Architecture Controls mRNA m6A Suppression and Gene Expression

(Submitter supplied) N6–methyladenosine (m6A) is the most abundant mRNA modification and plays crucial roles in diverse physiological processes. Utilizing a Massively Parallel Assay for m6A (MPm6A), we discover that m6A specificity is globally regulated by “suppressors” that prevent m6A deposition in unmethylated transcriptome regions. We identify Exon Junction Complexes (EJCs) as m6A suppressors that protect exon junction-proximal RNA within coding sequences from methylation and regulate mRNA stability through m6A suppression. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL20301 GPL18573 GPL24676
166 Samples
Download data: BED, BEDGRAPH, TXT
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

HeLa siControl Input rep1

Organism:
Homo sapiens
Source name:
Uterus
Platform:
GPL24676
Series:
GSE162199
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Sample
Accession:
GSM7045806
ID:
307045806
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db=gds|term=GSM7045806[Accession]|query=1|qty=2|blobid=MCID_675abbf02d96a1059646d6eb|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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