GSM702239[Accession] - GEO DataSets

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Items: 4

Select item 2000284181.

Expression data from mouse tissues and MEFs: insights into the physiological activation of p53-p66Shc pathway

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platforms:: GPL11180 GPL1261
40 Samples

Download data: CEL

Series

Accession:: GSE28418

ID:: 200028418

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000284162.

Expression data from mouse embryo fibroblast (MEFS)

(Submitter supplied) The role of p53 in assuring longevity through prevention of cancer is well established, but how it specifically regulates aging is still controversial. Our assumption is that distinct p53-pathways regulate tumor suppression and aging and that p66Shc is one of the master regulators of the p53 aging function. p66Shc longevity determinant protein acts as a downstream target of p53 and it is indispensable for the ability of activated p53 to induce elevation of intracellular oxidants and apoptosis. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11180
28 Samples

Download data: CEL

Series

Accession:: GSE28416

ID:: 200028416

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000111803.

[HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Protocol: see manufacturer's web site