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Items: 4

1.

Real-time Monitoring of Cisplatin Toxicity on Cancer Cells

(Submitter supplied) Treatment of MCF7 breast cancer cells by cisplatin leads to a very specific metabolic response and an onset of cell death about 10-11 h after beginning of treatment. For more detailed understanding of the molecular processes underlying the specific metabolic response, mRNA was isolated from MCF7 cells when the specific changes, (i) induction of glycolysis and (ii) onset of cell death, were detected during online measurement in the cell biosensor system.
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3910
Platform:
GPL570
6 Samples
Download data: CEL
Series
Accession:
GSE28274
ID:
200028274
2.
Full record GDS3910

Cisplatin effect on breast cancer cell line MCF-7: time course

Analysis of MCF-7 cell line treated with chemotheraputic agent cisplatin and collected when glycolysis was induced (change of ph; 8-9h) and at the beginning of cell death (change of impedance; 10-11h). Results provide insight into molecular mechanisms underlying the specific metabolic response.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 metabolism, 3 time sets
Platform:
GPL570
Series:
GSE28274
6 Samples
Download data: CEL
3.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...
Organism:
Homo sapiens
602 DataSets
5675 Series
61 Related Platforms
175722 Samples
Download data
Platform
Accession:
GPL570
ID:
100000570
4.

Impedance_change1

Organism:
Homo sapiens
Source name:
MCF-7 cells
Platform:
GPL570
Series:
GSE28274
Dataset:
GDS3910
Download data: CEL
Sample
Accession:
GSM699780
ID:
300699780
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db=gds|term=GSM699780[Accession]|query=1|qty=2|blobid=MCID_678f0115f521160690300080|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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