GEO DataSets

(Submitter supplied) DNA damage caused by UV radiation initiates cellular recovery mechanisms, which involve activation of DNA damage response pathways, cell cycle arrest and apoptosis. To assess cellular transcriptional responses to UVC-induced DNA damage we compared time course responses of human skin fibroblasts to low and high doses of UVC radiation known to induce a transient cellular replicative arrest or apoptosis, respectively. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS400

Platform:

GPL8300

20 Samples

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Temporal analysis of differences in WS1 human skin fibroblast gene expression response to low (10 J/m2; induces transient cellular replicative arrest) or high (50 J/m2; induces apoptosis) doses of short wavelength UV radiation (UVC; 254 nm).

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 protocol, 4 time sets

Platform:

GPL8300

Series:

GSE713

20 Samples

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(Submitter supplied) The transcriptional response to 50 J/m2 of UV-light (254 nm) was assessed with HGU95AV2 Affymetrix probe arrays at 6, 12, 18 and 24 hours after exposure. Mock-treated samples were assessed at 6 and 24 hours. Keywords: time-course

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL8300

12 Samples

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(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Based on this UniGene build and associated annotations, the HG-U95Av2 array represents approximately 10,000 full-length genes. more...

Organism:

Homo sapiens

99 DataSets

302 Series

6446 Samples

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