GSM674071[Accession] - GEO DataSets

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Items: 3

Select item 2000272661.

Fish oil/pectin temporally alters gene expression profiles in exfoliated rat colonocytes throughout oncogenesis

(Submitter supplied) We have demonstrated that fish oil/pectin (FO/P) diets protect against colon cancer compared to corn oil/cellulose (CO/C) by upregulating apoptosis and suppressing proliferation. To elucidate the mechanisms whereby FO/P diets induce apoptosis and suppress proliferation during the tumorigenic process, we analyzed the temporal gene expression profiles from exfoliated rat colonocytes. KEYWORDS: Fish oil/pectin, pectin, exfoliated colonocytes, gene expression, apoptosis, colon cancer, chemoprevention

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL2896
89 Samples

Download data: TXT

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Accession:: GSE27266

ID:: 200027266

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000028962.

GE Healthcare/Amersham Biosciences CodeLink™ Rat Whole Genome Bioarray

(Submitter supplied) Well-annotated mRNA or coding sequences were chosen to ensure usefulness for a large range of applications in basic research, biotechnology, and drug development. Each sequence was carefully screened to ensure high-quality, specific probe design, and to reduce redundancy of gene targets. All of the probes designed to these sequences were functionally tested, and over 95% were functionally validated against 10 rat tissues to ensure best representation of the gene and biologically relevant results. more...