GSM6666000[Accession] - GEO DataSets

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Items: 4

Select item 2002162901.

HDAC1 regulates the chromatin landscape to control transcriptional dependencies in chronic lymphocytic leukemia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platforms:: GPL18573 GPL20301
71 Samples

Download data: BROADPEAK, NARROWPEAK

Series

Accession:: GSE216290

ID:: 200216290

PubMed Full text in PMC Similar studies

Select item 2002162872.

HDAC1 regulates the chromatin landscape to control transcriptional dependencies in chronic lymphocytic leukemia [ChIP-seq]

(Submitter supplied) Chronic lymphocytic leukemia (CLL) is a quiescent B-cell malignancy that depends on transcriptional dysregulation for survival. The histone deacetylases are transcriptional regulators whose role within the regulatory chromatin and consequence on the CLL transcriptome is poorly characterized. Here, we profiled and integrated the genome wide occupancy of HDAC1, BRD4, H3K27Ac and H3K9Ac signals with chromatin accessibility, Pol2 occupancy and target expression signatures in CLL cells. more...