GEO DataSets

(Submitter supplied) Background: Septic shock is a heterogeneous syndrome within which probably exist several biological subclasses. Discovery and identification of septic shock subclasses could provide the foundation for the design of more specifically targeted therapies. Herein we tested the hypothesis that pediatric septic shock subclasses can be discovered through genome-wide expression profiling. Methods: Genome-wide expression profiling was conducted using whole blood-derived RNA from 98 children with septic shock, followed by a series of bioinformatic approaches targeted at subclass discovery and characterization. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4274

Platform:

GPL570

130 Samples

Download data: CEL

Analysis of whole blood from children (up to 10 years old) within 24hrs of PICU admission for septic shock. Heterogeneous clinical phenotypes stratify the septic shock patients. Results provide insight into the molecular mechanisms underlying these septic shock subgroups.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 4 development stage, 2 disease state, 4 other sets

Platform:

GPL570

Series:

GSE26440

130 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...

Organism:

Homo sapiens

602 DataSets

5670 Series

61 Related Platforms

175576 Samples

Download data