GEO DataSets

(Submitter supplied) Background: Septic shock heterogeneity has important implications for the conduct of clinical trials and individual patient management. We previously addressed this heterogeneity by indentifying 3 putative subclasses of children with septic shock based on a 100-gene expression signature corresponding to adaptive immunity and glucocorticoid receptor signaling. Herein we attempted to prospectively validate the existence of these gene expression-based subclasses in a validation cohort. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4273

Platform:

GPL570

103 Samples

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Analysis of whole blood from children (up to 10 years old) within 24hrs of PICU admission for septic shock. Sepsis therapies useful in adults and older children may have little effect in immunologically immature younger patients. Results provide insight into age-specific host response to sepsis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 4 development stage, 2 disease state, 2 other sets

Platform:

GPL570

Series:

GSE26378

103 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...

Organism:

Homo sapiens

602 DataSets

5670 Series

61 Related Platforms

175576 Samples

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