GSM637810[Accession] - GEO DataSets

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Items: 3

Select item 2000259731.

FGF2 sustains NANOG and switches the outcome of BMP4 induced human embryonic stem cell differentiation

(Submitter supplied) NANOG has emerged as a central gatekeeper of pluripotency. Here we show that as human embryonic stem (ES) cells exit the pluripotent state, NANOG can play a key role in determining lineage outcome. It has previously been reported that BMPs can induce differentiation of human ES cells into extraembryonic lineages. Here we report that FGF2 switches BMP4 induced differentiation outcome to mesendoderm, characterized by the uniform expression of T (brachyury) and other primitive streak markers. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL6602 GPL9999
50 Samples

Download data: PAIR

Series

Accession:: GSE25973

ID:: 200025973

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000066022.

HG17_Human_60mer_1in2

(Submitter supplied) See Roche NimbleGen website

Organism:: Homo sapiens

11 Series
504 Samples

Download data: NDF, NGD

Platform

Accession:: GPL6602

ID:: 100006602

Select item 3006378103.

H1 control in TeSR1 (Control_102540)

Organism:: Homo sapiens

Source name:: Undifferentiated H1 cells cultured in TeSR1 medium. The starting point of this experiment. (channel 1) undifferentiated H1 (channel 2)