GEO DataSets

(Submitter supplied) We used high density oligonucleotide arrays to measure the relative expression levels of >39,000 genes and ESTs in the NOD mouse (a murine model of T1D and other autoimmune conditions), four NOD-derived diabetes resistant congenic strains and two nondiabetic control strains. Owing to the importance of T cells in the development of T1D we decided to target two organs, the spleen and thymus. We profiled gene expression in thymi from four week old female mice and spleens from three month old female mice. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS10

Platform:

GPL24

28 Samples

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Examination of spleen and thymus of type 1 diabetes nonobese diabetic (NOD) mouse, four NOD-derived diabetes-resistant congenic strains and two nondiabetic control strains.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 disease state, 7 strain, 2 tissue sets

Platform:

GPL24

Series:

GSE11

28 Samples

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(Submitter supplied) Custom Affymetrix GeneChip designed by Eos Biotechnology Inc. to measure the expression of a large number of genes or ESTs on a single array. This is achieved by choosing those probes from within each set of 20 Affymetrix perfect match probes that show the least random fluctuation relative to the perceived specific hybridization over a wide ranging set of samples (Glynne et al. 2000). Experiments undertaken by Eos have revealed that the mismatch probes do not increase sensitivity or reproducibility (RJG and GG unpublished data). more...

Organism:

Mus musculus

1 DataSet

3 Series

28 Samples

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